Protein: CC14B
Dual specificity protein phosphatase CDC14B (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog B)

Gene: CC14B, CDC14B
Organism: Homo sapiens
Interactions: 155
UniProt ID: O60729

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0000922 - spindle pole
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

254314

CC14B
Dual specificity protein phosphatase CDC14B

1

15

High-throughput

0.618

High

254338

MSH2
DNA mismatch repair protein Msh2

2

5

High-throughput

0.614

High

225503

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

1

High-throughput

0.606

High

254327

PSB1
Proteasome subunit beta type-1

2

4

High-throughput

0.606

High

254344

MFAP1
Microfibrillar-associated protein 1

2

1

High-throughput

0.606

High

254431

ZN696
Zinc finger protein 696

2

2

High-throughput

0.606

High

254362

SKP2
S-phase kinase-associated protein 2

2

5

Small-scale

0.595

High

163018

CHK1
Serine/threonine-protein kinase Chk1

1

3

Small-scale

0.561

High

254321

P53
Cellular tumor antigen p53

1

5

Small-scale

0.561

High

224062

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

10

High-throughput

0.541

High

254328

CRCM
Colorectal mutant cancer protein

1

5

High-throughput

0.541

High

254329

CCND1
G1/S-specific cyclin-D1

1

5

High-throughput

0.541

High

254374

STK11
Serine/threonine-protein kinase STK11

1

6

High-throughput

0.541

High

254413

RHG07
Rho GTPase-activating protein 7

1

9

High-throughput

0.541

High

254447

MLH3
DNA mismatch repair protein Mlh3

1

2

High-throughput

0.541

High

171131

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

13

High-throughput

0.536

High

177146

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

8

High-throughput

0.536

High

254317

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

7

High-throughput

0.536

High

254368

PSF1
DNA replication complex GINS protein PSF1

1

1

High-throughput

0.536

High

254408

SAHH3
Adenosylhomocysteinase 3

1

9

High-throughput

0.536

High

254410

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

12

High-throughput

0.536

High

254417

SLD5
DNA replication complex GINS protein SLD5

1

1

High-throughput

0.536

High

254418

PSF3
DNA replication complex GINS protein PSF3

1

1

High-throughput

0.536

High

254436

TRI36
E3 ubiquitin-protein ligase TRIM36

1

15

High-throughput

0.536

High

254442

DCA16
DDB1- and CUL4-associated factor 16

1

1

High-throughput

0.536

High

254451

PSF2
DNA replication complex GINS protein PSF2

1

1

High-throughput

0.536

High

254319

BCL10
B-cell lymphoma/leukemia 10

1

0

High-throughput

0.518

High

254363

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.518

High

254384

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

5

Small-scale

0.515

High

254446

GRHPR
Glyoxylate reductase/hydroxypyruvate reductase

1

3

High-throughput

0.515

High

254449

FZR1
Fizzy-related protein homolog

1

11

Small-scale

0.515

High

254459

RL36
Large ribosomal subunit protein eL36

1

1

High-throughput

0.515

High

254339

KPB2
Phosphorylase b kinase regulatory subunit alpha, liver isoform

1

0

High-throughput

0.513

High

254357

HMCS1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic

1

0

High-throughput

0.513

High

254386

THNS1
Threonine synthase-like 1

1

0

High-throughput

0.513

High

254388

ANR44
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B

1

8

High-throughput

0.489

High

254391

ANR52
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

1

8

High-throughput

0.489

High

254448

ANR50
Ankyrin repeat domain-containing protein 50

1

8

High-throughput

0.489

High

254337

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

15

High-throughput

0.481

High

139447

PESC
Pescadillo homolog

1

1

High-throughput

0.479

High

220831

XPOT
Exportin-T

1

15

High-throughput

0.479

High

222566

PRC1
Protein regulator of cytokinesis 1

1

7

High-throughput

0.479

High

254316

PHF2
Lysine-specific demethylase PHF2

1

4

High-throughput

0.479

High

254320

NSD2
Histone-lysine N-methyltransferase NSD2

1

8

High-throughput

0.479

High

254322

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.479

High

254323

HMGB1
High mobility group protein B1

1

8

High-throughput

0.479

High

254325

UBF1
Nucleolar transcription factor 1

1

6

High-throughput

0.479

High

254330

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

254331

BRD2
Bromodomain-containing protein 2

1

5

High-throughput

0.479

High

254332

DNMT1
DNA

1

4

High-throughput

0.479

High

254333

T2EA
General transcription factor IIE subunit 1

1

1

High-throughput

0.479

High

254334

T2FA
General transcription factor IIF subunit 1

1

3

High-throughput

0.479

High

254335

DEK
Protein DEK

1

1

High-throughput

0.479

High

254336

SRP14
Signal recognition particle 14 kDa protein

1

1

High-throughput

0.479

High

254340

RM19
Large ribosomal subunit protein bL19m

1

1

High-throughput

0.479

High

254341

MSH6
DNA mismatch repair protein Msh6

1

8

High-throughput

0.479

High

254342

MK12
Mitogen-activated protein kinase 12

1

20

Small-scale

0.479

High

254345

MAZ
Myc-associated zinc finger protein

1

2

High-throughput

0.479

High

254346

RL26
Large ribosomal subunit protein uL24

1

2

High-throughput

0.479

High

254347

CSK21
Casein kinase II subunit alpha

1

14

High-throughput

0.479

High

254348

NOP14
Nucleolar protein 14

1

1

High-throughput

0.479

High

254352

RT15
Small ribosomal subunit protein uS15m

1

1

High-throughput

0.479

High

254356

TFAM
Transcription factor A, mitochondrial

1

4

High-throughput

0.479

High

254358

CENPC
Centromere protein C

1

5

High-throughput

0.479

High

254360

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.479

High

254361

SRSF9
Serine/arginine-rich splicing factor 9

1

4

High-throughput

0.479

High

254364

NOG2
Nucleolar GTP-binding protein 2

1

5

High-throughput

0.479

High

254365

CIRBP
Cold-inducible RNA-binding protein

1

7

High-throughput

0.479

High

254366

ELOA1
Elongin-A

1

4

High-throughput

0.479

High

254367

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.479

High

254369

BMS1
Ribosome biogenesis protein BMS1 homolog

1

6

High-throughput

0.479

High

254370

CBX2
Chromobox protein homolog 2

1

4

High-throughput

0.479

High

254371

KIF22
Kinesin-like protein KIF22

1

11

High-throughput

0.479

High

254372

BRD3
Bromodomain-containing protein 3

1

6

High-throughput

0.479

High

254373

ZN174
Zinc finger protein 174

1

3

High-throughput

0.479

High

254375

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

3

High-throughput

0.479

High

254376

GLYR1
Cytokine-like nuclear factor N-PAC

1

5

High-throughput

0.479

High

254379

RRP12
RRP12-like protein

1

2

High-throughput

0.479

High

254381

ZN362
Zinc finger protein 362

1

2

High-throughput

0.479

High

254383

AROS
Active regulator of SIRT1

1

3

High-throughput

0.479

High

254385

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

8

High-throughput

0.479

High

254389

KRI1
Protein KRI1 homolog

1

4

High-throughput

0.479

High

254390

PR38A
Pre-mRNA-splicing factor 38A

1

1

High-throughput

0.479

High

254392

RN169
E3 ubiquitin-protein ligase RNF169

1

6

High-throughput

0.479

High

254393

Z280C
Zinc finger protein 280C

1

1

High-throughput

0.479

High

254395

SRFB1
Serum response factor-binding protein 1

1

2

High-throughput

0.479

High

254396

G45IP
Large ribosomal subunit protein mL64

1

3

High-throughput

0.479

High

254397

NOC3L
Nucleolar complex protein 3 homolog

1

2

High-throughput

0.479

High

254398

CATIN
Splicing factor Cactin

1

2

High-throughput

0.479

High

254399

ZKSC4
Zinc finger protein with KRAB and SCAN domains 4

1

2

High-throughput

0.479

High

254400

RL36L
Ribosomal protein eL42-like

1

3

High-throughput

0.479

High

254401

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

1

High-throughput

0.479

High

254402

NUD16
U8 snoRNA-decapping enzyme

1

1

High-throughput

0.479

High

254405

AURKB
Aurora kinase B

1

10

High-throughput

0.479

High

254406

DDX27
Probable ATP-dependent RNA helicase DDX27

1

7

High-throughput

0.479

High

254409

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

1

High-throughput

0.479

High

254411

Z512B
Zinc finger protein 512B

1

2

High-throughput

0.479

High

254412

ZN512
Zinc finger protein 512

1

3

High-throughput

0.479

High

254414

ATAD5
ATPase family AAA domain-containing protein 5

1

6

High-throughput

0.479

High

254415

DDX50
ATP-dependent RNA helicase DDX50

1

4

High-throughput

0.479

High

254416

MBB1A
Myb-binding protein 1A

1

3

High-throughput

0.479

High

254420

NOC4L
Nucleolar complex protein 4 homolog

1

2

High-throughput

0.479

High

254423

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

6

High-throughput

0.479

High

254424

RT26
Small ribosomal subunit protein mS26

1

1

High-throughput

0.479

High

254425

NSD3
Histone-lysine N-methyltransferase NSD3

1

12

High-throughput

0.479

High

254432

DDX31
ATP-dependent DNA helicase DDX31

1

4

High-throughput

0.479

High

254434

CBX8
Chromobox protein homolog 8

1

4

High-throughput

0.479

High

254438

HELLS
Lymphoid-specific helicase

1

4

High-throughput

0.479

High

254443

AATF
Protein AATF

1

3

High-throughput

0.479

High

254444

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.479

High

254445

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

2

High-throughput

0.479

High

254450

PHF8
Histone lysine demethylase PHF8

1

3

High-throughput

0.479

High

254457

RT16
Small ribosomal subunit protein bS16m

1

1

High-throughput

0.479

High

254318

WIZ
Protein Wiz

1

0

High-throughput

0.458

High

254324

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.458

High

254326

XRCC1
DNA repair protein XRCC1

1

0

High-throughput

0.458

High

254343

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.458

High

254359

CEBPZ
CCAAT/enhancer-binding protein zeta

1

0

High-throughput

0.458

High

254378

BOREA
Borealin

1

0

High-throughput

0.458

High

254382

CDCA2
Cell division cycle-associated protein 2

1

0

High-throughput

0.458

High

254407

ZCCHL
Zinc finger CCCH-type antiviral protein 1-like

1

0

High-throughput

0.458

High

254419

NOL10
Nucleolar protein 10

1

0

High-throughput

0.458

High

254421

NUSAP
Nucleolar and spindle-associated protein 1

1

0

High-throughput

0.458

High

254426

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.458

High

254427

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

0

High-throughput

0.458

High

254428

RM46
Large ribosomal subunit protein mL46

1

0

High-throughput

0.458

High

254429

ESF1
ESF1 homolog

1

0

High-throughput

0.458

High

254430

CCD86
Coiled-coil domain-containing protein 86

1

0

High-throughput

0.458

High

254433

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

1

0

High-throughput

0.458

High

254437

SAS10
Something about silencing protein 10

1

0

High-throughput

0.458

High

254439

SDA1
Protein SDA1 homolog

1

0

High-throughput

0.458

High

254441

TEX10
Testis-expressed protein 10

1

0

High-throughput

0.458

High

254456

NOP16
Nucleolar protein 16

1

0

High-throughput

0.458

High

254387

ARF
Tumor suppressor ARF

1

0

High-throughput

0.438

High

254349

RT25
Small ribosomal subunit protein mS25

1

1

High-throughput

0.437

High

254350

RT10
Small ribosomal subunit protein uS10m

1

2

High-throughput

0.437

High

254351

RT11
Small ribosomal subunit protein uS11m

1

1

High-throughput

0.437

High

254353

RT21
Small ribosomal subunit protein bS21m

1

1

High-throughput

0.437

High

254394

LY65B
Lymphocyte antigen 6 complex locus protein G5b

1

1

High-throughput

0.437

High

254422

RM13
Large ribosomal subunit protein uL13m

1

3

High-throughput

0.437

High

254453

RT28
Small ribosomal subunit protein bS1m

1

2

High-throughput

0.437

High

254454

RT07
Small ribosomal subunit protein uS7m

1

4

High-throughput

0.437

High

254455

RT02
Small ribosomal subunit protein uS2m

1

2

High-throughput

0.437

High

254458

RT23
Small ribosomal subunit protein mS23

1

1

High-throughput

0.437

High

254380

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

2

0

High-throughput

0.316

High

254377

CE022
UPF0489 protein C5orf22

1

0

High-throughput

0.279

Low

254315

RT14
Small ribosomal subunit protein uS14m

1

0

High-throughput

0.249

Low

254354

RT34
Small ribosomal subunit protein mS34

1

0

High-throughput

0.249

Low

254355

RT06
Small ribosomal subunit protein bS6m

1

0

High-throughput

0.249

Low

254403

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.249

Low

254404

RM48
Large ribosomal subunit protein mL48

1

0

High-throughput

0.249

Low

254435

RM47
Large ribosomal subunit protein uL29m

1

0

High-throughput

0.249

Low

254440

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.249

Low

254452

RT33
Small ribosomal subunit protein mS33

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025