HitPredict

Interactor 1: EF1B (P24534)
Elongation factor 1-beta (EF-1-beta)
Gene: EEF1B2

Interactor 2: EF1A1 (P68104)
Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)
Gene: EEF1A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

Property	Details
Experiments	37071682, 28514442, 33961781, 35235311
Identification Methods	cross-linking study, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF1_GNE~GTP_EFTU, EF1_GNE~GTP_EFTU_D2
Common GO terms	GO:0003746 - translation elongation factor activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005853 - eukaryotic translation elongation factor 1 complex GO:0006414 - translational elongation
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 225 Hs			1 462
+	Hs
		623107 EF1B_HUMAN (1-225): 2.59e-105: 304: 100.00		EF1A2_HUMAN (1-461): 0: 567: 92.63
+	Hs
		669331 EF1D_HUMAN (52-225): 9.96e-73: 224: 64.41		EF1A1_HUMAN (1-462): 0: 578: 100.00
+	Hs
		669343 EF1D_HUMAN (52-225): 9.96e-73: 224: 64.41		EF1A2_HUMAN (1-461): 0: 567: 92.63
+	Sc
		367850 EF1B_YEAST (1-225): 1.1e-61: 193: 46.02		EF1A_YEAST (1-445): 0: 538: 80.90
+	Dm
		399196 EF1D_DROME (79-225): 1.32e-52: 171: 58.50		EF1A2_DROME (1-452): 0: 549: 85.18