Interactor 1: EME2 (A4GXA9)
Structure-specific endonuclease subunit EME2 (Essential meiotic structure-specific endonuclease subunit 2)
Gene: EME2
Interactor 2: MUS81 (Q96NY9)
Structure-specific endonuclease subunit MUS81 (EC 3.1.22.-) (Crossover junction endonuclease MUS81) (MUS81 endonuclease homolog)
Gene: MUS81
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.46 | 1.00 | 0.681 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17289582 |
| Identification Methods | pull down |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EME1-MUS81_C~EME1-MUS81_C, ERCC4~ERCC4 |
| Common GO terms | GO:0000712 - resolution of meiotic recombination intermediates GO:0003677 - DNA binding GO:0004519 - endonuclease activity GO:0006302 - double-strand break repair GO:0031297 - replication fork processing and 4 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
