Interactor 1: SPEE (P19623)
Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase)
Gene: SRM
Interactor 2: SPEE (P19623)
Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase)
Gene: SRM
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.83 | 1.00 | 0.912 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 31515488, 29892012, unassigned1304, 17585781 |
| Identification Methods | two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid, x-ray crystallography |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Spermine_synt_N~Spermine_synt_N, Spermine_synt_N~Spermine_synth, Spermine_synth~Spermine_synth |
| Common GO terms | GO:0004766 - spermidine synthase activity GO:0005829 - cytosol GO:0006595 - polyamine metabolic process GO:0008295 - spermidine biosynthetic process GO:0042803 - protein homodimerization activity and 1 others more... |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
