Interactor 1: SPSY (P52788)
Spermine synthase (SPMSY) (EC 2.5.1.22) (Spermidine aminopropyltransferase)
Gene: SMS
Interactor 2: SPSY (P52788)
Spermine synthase (SPMSY) (EC 2.5.1.22) (Spermidine aminopropyltransferase)
Gene: SMS
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31839598 |
| Identification Methods | cross-linking study |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Spermine_synt_N~Spermine_synt_N, Spermine_synt_N~Spermine_synth, Spermine_synt_N~SpmSyn_N, Spermine_synth~Spermine_synth, SpmSyn_N~SpmSyn_N |
| Common GO terms | GO:0005829 - cytosol GO:0006555 - methionine metabolic process GO:0006595 - polyamine metabolic process GO:0006597 - spermine biosynthetic process GO:0016768 - spermine synthase activity and 1 others more... |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
