HitPredict

Interactor 1: SL9A1 (P19634)
Sodium/hydrogen exchanger 1 (APNH) (Na(+)/H(+) antiporter, amiloride-sensitive) (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1)
Gene: SLC9A1

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	11279064, 16717153
Identification Methods	pull down, filter binding, experimental interaction detection, coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005925 - focal adhesion GO:0016020 - membrane GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0048471 - perinuclear region of cytoplasm and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 815 Hs			1 246
+	Hs
		624625 SL9A1_HUMAN (1-815): 0: 825: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		972095 SL9A2_HUMAN (85-799): 0: 663: 47.00		1433E_HUMAN (3-243): 4.41e-144: 405: 65.43
+	Hs
		730323 SL9A2_HUMAN (85-799): 0: 663: 47.00		1433B_HUMAN (1-246): 3.49e-144: 404: 100.00
+	Hs
		990831 SL9A2_HUMAN (85-799): 0: 663: 47.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		691513 SL9A2_HUMAN (85-799): 0: 663: 47.00		1433T_HUMAN (3-244): 3.25e-127: 361: 81.82
+	Hs
		966979 SL9A2_HUMAN (85-799): 0: 663: 47.00		1433G_HUMAN (3-246): 1.92e-109: 317: 75.40
+	Hs
		1049873 SL9A2_HUMAN (85-799): 0: 663: 47.00		1433F_HUMAN (4-244): 2.72e-107: 311: 75.51
+	Hs
		729843 SL9A5_HUMAN (75-713): 2.14e-173: 524: 40.30		1433B_HUMAN (1-246): 3.49e-144: 404: 100.00