Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2
Interactor 2: CDKN3 (Q16667)
Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.16) (EC 3.1.3.48) (CDK2-associated dual-specificity phosphatase) (Cyclin-dependent kinase interactor 1) (Cyclin-dependent kinase-interacting protein 2) (Kinase-associated phosphatase)
Gene: CDKN3
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.982 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25852190, 26186194, 28514442, 8127873, 8242751, 33961781, 12745075, 15530371, 11463386, 8242750, 24218572, 9840943 |
| Identification Methods | affinity chromatography technology, two hybrid, enzymatic study, phosphatase assay, x-ray crystallography, genetic interference, anti tag coimmunoprecipitation, lexa b52 complementation, coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association, dephosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CDKN3~Pkinase |
| Common GO terms | GO:0000082 - G1/S transition of mitotic cell cycle GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
