HitPredict

Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.747

The method score is based on:

Property Details
Experiments 28514442, 33306668, 33961781, 26083744, 11340163, 23972993, 23670162
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006281 - DNA repair
GO:0007346 - regulation of mitotic cell cycle
and 2 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 298
Hs

1 496
+ Dm
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ At
+ At
+ Hs
+ At
+ Hs
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024