Interactor 1: SPTC1 (P25045)
Serine palmitoyltransferase 1 (SPT 1) (SPT1) (EC 2.3.1.50) (Long chain base biosynthesis protein 1)
Gene: LCB1
Interactor 2: LCB2 (P40970)
Serine palmitoyltransferase 2 (SPT 2) (EC 2.3.1.50) (Long chain base biosynthesis protein 2)
Gene: LCB2
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.975 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20182505, 11805826, 10713067, 11781309, 16429126, 30529276, 37794019, 37982431, 38285738, 37968396 |
| Identification Methods | anti tag coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, pull down, biochemical, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Aminotran_1_2~Aminotran_1_2 |
| Common GO terms | GO:0004758 - serine C-palmitoyltransferase activity GO:0005783 - endoplasmic reticulum GO:0030170 - pyridoxal phosphate binding GO:0046512 - sphingosine biosynthetic process GO:0046513 - ceramide biosynthetic process and 1 others more... |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
