HitPredict

Interactor 1: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	36931259, 15161933
Identification Methods	proximity labelling technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2843 Hs			1 245
+	Hs
		626091 APC_HUMAN (1-2843): 0: 1316: 100.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		626093 APC_HUMAN (1-2843): 0: 1316: 100.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		626055 APC_HUMAN (1-2843): 0: 1316: 100.00		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		626056 APC_HUMAN (1-2843): 0: 1316: 100.00		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		626106 APC_HUMAN (1-2843): 0: 1316: 100.00		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		626089 APC_HUMAN (1-2843): 0: 1316: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		257595 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		257566 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		257597 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		257572 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		909649 ZEP3_HUMAN (802-2843): 1.1e-49: 198: 8.77		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		646967 ZEP3_HUMAN (802-2843): 1.1e-49: 198: 8.77		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927133 ZEP3_HUMAN (802-2843): 1.1e-49: 198: 8.77		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683415 ZEP3_HUMAN (802-2843): 1.1e-49: 198: 8.77		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		257573 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		257604 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		257593 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		684093 ZEP3_HUMAN (802-2843): 1.1e-49: 198: 8.77		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		982101 ZEP3_HUMAN (802-2843): 1.1e-49: 198: 8.77		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		904674 ZEP3_HUMAN (802-2843): 1.1e-49: 198: 8.77		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33