Protein: PARP4
Protein mono-ADP-ribosyltransferase PARP4 (EC 2.4.2.-) (193 kDa vault protein) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) (Poly [ADP-ribose] polymerase 4) (PARP-4) (Vault poly(ADP-ribose) polymerase) (VPARP)

Gene: PARP4
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q9UKK3

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003950 - NAD+ poly-ADP-ribosyltransferase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1132013

MVP
Major vault protein

4

0

Small-scale

0.670

High

1340836

COP1
E3 ubiquitin-protein ligase COP1

2

3

Small-scale

0.628

High

799564

BRCA1
Breast cancer type 1 susceptibility protein

1

7

High-throughput

0.618

High

1436544

ECT2
Protein ECT2

1

2

High-throughput

0.618

High

821619

TCPZ
T-complex protein 1 subunit zeta

1

1

High-throughput

0.541

High

765985

BMI1
Polycomb complex protein BMI-1

1

8

High-throughput

0.536

High

1124568

MAP7
Ensconsin

1

6

High-throughput

0.536

High

1380367

ZKSC4
Zinc finger protein with KRAB and SCAN domains 4

1

5

High-throughput

0.536

High

1330657

TPRX1
Tetra-peptide repeat homeobox protein 1

1

2

High-throughput

0.515

High

1026274

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.513

High

1433713

EMRE
Essential MCU regulator, mitochondrial

1

0

High-throughput

0.513

High

1435433

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

1460928

CCNL1
Cyclin-L1

1

0

High-throughput

0.513

High

668796

CO8A2
Collagen alpha-2(VIII) chain

1

1

High-throughput

0.489

High

1416848

C1QT2
Complement C1q tumor necrosis factor-related protein 2

1

1

High-throughput

0.489

High

1014653

SMAD3
Mothers against decapentaplegic homolog 3

1

1

High-throughput

0.481

High

257012

H2B1K
Histone H2B type 1-K

1

18

High-throughput

0.479

High

346474

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

5

High-throughput

0.479

High

404530

GCR
Glucocorticoid receptor

1

11

High-throughput

0.479

High

659953

H2B1O
Histone H2B type 1-O

1

18

High-throughput

0.479

High

872870

SOX2
Transcription factor SOX-2

1

11

High-throughput

0.479

High

1106745

SMAD4
Mothers against decapentaplegic homolog 4

1

1

High-throughput

0.479

High

1220881

RN123
E3 ubiquitin-protein ligase RNF123

1

3

High-throughput

0.479

High

1256033

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

1372337

H2B1H
Histone H2B type 1-H

1

18

High-throughput

0.479

High

1404492

CDC5L
Cell division cycle 5-like protein

1

4

High-throughput

0.479

High

1408451

TEP1
Telomerase protein component 1

1

4

Small-scale

0.479

High

1429971

RNF38
E3 ubiquitin-protein ligase RNF38

1

2

Small-scale

0.479

High

1447000

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

1461115

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.479

High

1461116

MYO6
Unconventional myosin-VI

1

1

High-throughput

0.479

High

171939

ZN263
Zinc finger protein 263

1

0

Small-scale

0.458

High

418508

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

766228

NOS2
Nitric oxide synthase, inducible

1

0

High-throughput

0.458

High

1136700

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.458

High

1178455

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1339223

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

564537

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.445

High

1326140

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.445

High

1250212

LRC31
Leucine-rich repeat-containing protein 31

1

3

High-throughput

0.437

High

384212

CO1A1
Collagen alpha-1(I) chain

1

0

Small-scale

0.426

High

1111347

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.426

High

1461117

COLQ
Acetylcholinesterase collagenic tail peptide

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025