Interactor 1: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Interactor 2: CTNA1 (P35221)
Catenin alpha-1 (Alpha E-catenin) (Cadherin-associated protein) (Renal carcinoma antigen NY-REN-13)
Gene: CTNNA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.731

The method score is based on:

Property Details
Experiments 34079125, 26496610, 29045831, 8259519, 7651399, 20936779
Identification Methods proximity labelling technology, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005912 - adherens junction
GO:0007155 - cell adhesion
GO:0008013 - beta-catenin binding
and 4 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 2843
Hs

1 906
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024