HitPredict

Interactor 1: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Interactor 2: DVLP1 (P54792)
Putative segment polarity protein dishevelled homolog DVL1P1 (DSH homolog 1-like) (Segment polarity protein dishevelled homolog DVL-1-like) (Dishevelled-1-like)
Gene: DVL1P1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	20224554
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2843 Hs			1 670
+	Hs
		150673 APC_HUMAN (1-2843): 0: 1316: 100.00		DVL1_HUMAN (1-670): 3.04e-147: 445: 92.81
+	Hs
		150855 APC_HUMAN (1-2843): 0: 1316: 100.00		DVL2_HUMAN (3-670): 7.02e-109: 347: 55.91
+	Hs
		626083 APC_HUMAN (1-2843): 0: 1316: 100.00		AFAD_HUMAN (245-641): 8.73e-84: 291: 21.55
+	Mm
		1141494 APC_MOUSE (1-2843): 0: 1220: 89.82		DVL2_MOUSE (3-670): 1.03e-111: 354: 56.87
+	Hs
		626115 APC_HUMAN (1-2843): 0: 1316: 100.00		DLG1_HUMAN (46-598): 2.85e-63: 227: 13.94
+	Rn
		677772 APC_RAT (1-2843): 0: 1222: 89.60		DLG4_RAT (100-622): 5.74e-70: 243: 15.57
+	Mm
		1142526 APC_MOUSE (1-2843): 0: 1220: 89.82		DLG4_MOUSE (100-622): 1.07e-69: 242: 15.93
+	Hs
		626216 APC_HUMAN (1-2843): 0: 1316: 100.00		DLG3_HUMAN (236-628): 1.68e-24: 111: 13.10
+	Hs
		626207 APC_HUMAN (1-2843): 0: 1316: 100.00		PARD3_HUMAN (93-637): 6.02e-18: 90.6: 11.86
+	Hs
		626113 APC_HUMAN (1-2843): 0: 1316: 100.00		PTN13_HUMAN (12-432): 1.48e-13: 76.7: 13.75
+	Ce
		1094130 APR1_CAEEL (274-1464): 5.62e-115: 399: 16.91		MIG5_CAEEL (2-476): 5.07e-61: 218: 27.12
+	Hs
		151109 TITIN_HUMAN (717-2430): 7.06e-29: 130: 7.55		DVL2_HUMAN (3-670): 7.02e-109: 347: 55.91
+	Hs
		876457 TITIN_HUMAN (717-2430): 7.06e-29: 130: 7.55		AFAD_HUMAN (245-641): 8.73e-84: 291: 21.55
+	Mm
		57254 NACAM_MOUSE (703-2637): 1.09e-53: 211: 8.91		A2AKD7_MOUSE (173-564): 1.35e-47: 177: 15.27
+	Mm
		1143541 MAP1A_MOUSE (738-2466): 8.19e-18: 93.6: 8.21		DLG4_MOUSE (100-622): 1.07e-69: 242: 15.93
+	Hs
		942322 MAP1A_HUMAN (907-2836): 5.17e-16: 87.6: 8.68		DLG4_HUMAN (100-622): 6.82e-70: 243: 15.57
+	Mm
		1143421 ANK2_MOUSE (1056-2841): 1.1e-15: 86.5: 9.74		DLG4_MOUSE (100-622): 1.07e-69: 242: 15.93
+	Hs
		944681 MAP1A_HUMAN (907-2836): 5.17e-16: 87.6: 8.68		DLG2_HUMAN (47-622): 9.83e-68: 240: 11.89
+	Hs
		944673 MAP1A_HUMAN (907-2836): 5.17e-16: 87.6: 8.68		DLG1_HUMAN (46-598): 2.85e-63: 227: 13.94
+	Hs
		1256852 TITIN_HUMAN (717-2430): 7.06e-29: 130: 7.55		PARD3_HUMAN (93-637): 6.02e-18: 90.6: 11.86