HitPredict

Interactor 1: MCM3 (P25205)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102)
Gene: MCM3

Interactor 2: UHRF1 (Q96T88)
E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Inverted CCAAT box-binding protein of 90 kDa) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (HuNp95) (hNp95) (RING finger protein 106) (RING-type E3 ubiquitin transferase UHRF1) (Transcription factor ICBP90) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (hUHRF1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)
Gene: UHRF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28803780
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 808 Hs			1 793
+	Hs
		627247 MCM3_HUMAN (1-808): 0: 944: 100.00		CHD3_HUMAN (101-502): 7.48e-52: 198: 13.90
+	Hs
		627266 MCM3_HUMAN (1-808): 0: 944: 100.00		CHD4_HUMAN (233-502): 9.71e-49: 189: 15.00
+	Hs
		832409 MCM2_HUMAN (10-721): 0: 707: 30.62		CHD3_HUMAN (101-502): 7.48e-52: 198: 13.90
+	Hs
		708618 MCM5_HUMAN (9-713): 0: 685: 28.92		CHD3_HUMAN (101-502): 7.48e-52: 198: 13.90
+	Hs
		1055555 MCM6_HUMAN (2-800): 0: 688: 26.50		CHD4_HUMAN (233-502): 9.71e-49: 189: 15.00
+	Hs
		708880 MCM7_HUMAN (10-669): 0: 650: 31.62		CHD3_HUMAN (101-502): 7.48e-52: 198: 13.90
+	Hs
		832455 MCM2_HUMAN (10-721): 0: 707: 30.62		TRI25_HUMAN (715-786): 9.14e-20: 96.1: 31.08
+	Hs
		708903 MCM7_HUMAN (10-669): 0: 650: 31.62		TRI25_HUMAN (715-786): 9.14e-20: 96.1: 31.08