Protein: CLIC1
Chloride intracellular channel protein 1 (Chloride channel ABP) (Nuclear chloride ion channel 27) (NCC27) (Regulatory nuclear chloride ion channel protein) (hRNCC)

Gene: CLIC1
Organism: Homo sapiens
Interactions: 121
UniProt ID: O00299

Gene Ontology (top 5):
GO:0005254 - chloride channel activity
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

124563

CFTR
Cystic fibrosis transmembrane conductance regulator

4

1

High-throughput

0.700

High

124617

TPRN
Taperin

4

3

High-throughput

0.698

High

124535

LSM1
U6 snRNA-associated Sm-like protein LSm1

4

0

Small-scale

0.661

High

124538

PRKN
E3 ubiquitin-protein ligase parkin

3

5

High-throughput

0.640

High

124645

ANLN
Anillin

3

0

High-throughput

0.628

High

124644

SDF2L
Stromal cell-derived factor 2-like protein 1

2

0

High-throughput

0.602

High

124542

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

1

Small-scale

0.597

High

124540

BRD4
Bromodomain-containing protein 4

2

1

High-throughput

0.584

High

124545

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

124625

PRSR2
Proline and serine-rich protein 2

2

1

High-throughput

0.574

High

124549

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

124615

KPCD1
Serine/threonine-protein kinase D1

2

1

High-throughput

0.571

High

124619

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

4

High-throughput

0.571

High

124558

TPC2B
Trafficking protein particle complex subunit 2B

1

1

Small-scale

0.552

High

124569

VCAM1
Vascular cell adhesion protein 1

2

0

High-throughput

0.547

High

124559

THA
Thyroid hormone receptor alpha

1

2

High-throughput

0.541

High

124637

ZN184
Zinc finger protein 184

1

2

High-throughput

0.541

High

124647

ZN302
Zinc finger protein 302

1

1

High-throughput

0.541

High

124652

NEMO
NF-kappa-B essential modulator

1

1

High-throughput

0.541

High

124536

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

3

High-throughput

0.536

High

124547

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.536

High

124565

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

1

High-throughput

0.536

High

124646

MYO5C
Unconventional myosin-Vc

1

2

High-throughput

0.536

High

124628

SH2D3
SH2 domain-containing protein 3C

2

4

High-throughput

0.521

High

124556

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.518

High

124570

AL5AP
Arachidonate 5-lipoxygenase-activating protein

1

0

High-throughput

0.518

High

124572

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

1

0

High-throughput

0.518

High

124575

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.518

High

124580

NTF4
Neurotrophin-4

1

0

High-throughput

0.518

High

124587

NUP62
Nuclear pore glycoprotein p62

1

0

High-throughput

0.518

High

124597

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

High-throughput

0.518

High

124633

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.518

High

124622

Q6FHY5
MEOX2 protein

1

2

High-throughput

0.515

High

48583

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.513

High

124534

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.513

High

124579

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.513

High

124583

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.513

High

124586

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

High-throughput

0.513

High

124592

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

High-throughput

0.513

High

124593

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.513

High

124627

SYNPO
Synaptopodin

1

0

High-throughput

0.513

High

124651

HPSE
Heparanase

1

0

High-throughput

0.513

High

124596

MEOX2
Homeobox protein MOX-2

1

2

High-throughput

0.481

High

124608

PRDX4
Peroxiredoxin-4

1

1

High-throughput

0.481

High

124543

TRI37
E3 ubiquitin-protein ligase TRIM37

1

3

High-throughput

0.479

High

124544

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.479

High

124548

FINC
Fibronectin

1

3

High-throughput

0.479

High

124550

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.479

High

124553

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

124555

ISG15
Ubiquitin-like protein ISG15

1

6

High-throughput

0.479

High

124560

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

124561

EPB41
Protein 4.1

1

2

High-throughput

0.479

High

124566

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

124568

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.479

High

124571

CRCM
Colorectal mutant cancer protein

1

1

High-throughput

0.479

High

124573

CDK2
Cyclin-dependent kinase 2

1

1

High-throughput

0.479

High

124574

U2AF2
Splicing factor U2AF 65 kDa subunit

1

1

High-throughput

0.479

High

124576

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

124578

CCND2
G1/S-specific cyclin-D2

1

1

Small-scale

0.479

High

124581

GRK5
G protein-coupled receptor kinase 5

1

1

High-throughput

0.479

High

124582

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

1

High-throughput

0.479

High

124585

HNF1B
Hepatocyte nuclear factor 1-beta

1

1

High-throughput

0.479

High

124591

YAP1
Transcriptional coactivator YAP1

1

2

High-throughput

0.479

High

124598

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

124599

HDAC4
Histone deacetylase 4

1

1

High-throughput

0.479

High

124601

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

124602

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

124614

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

124623

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

124630

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.479

High

124631

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

124632

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

124642

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

124649

HDAC6
Histone deacetylase 6

1

1

High-throughput

0.479

High

124650

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

124639

MYOC
Myocilin

1

0

Small-scale

0.460

High

124537

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

124539

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

124541

PPM1B
Protein phosphatase 1B

1

0

High-throughput

0.458

High

124546

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

124562

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

124564

ITA4
Integrin alpha-4

1

0

High-throughput

0.458

High

124567

IL7RA
Interleukin-7 receptor subunit alpha

1

0

High-throughput

0.458

High

124577

CDC27
Cell division cycle protein 27 homolog

1

0

Small-scale

0.458

High

124588

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

124594

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

124603

RHOB
Rho-related GTP-binding protein RhoB

1

0

High-throughput

0.458

High

124604

VIGLN
Vigilin

1

0

High-throughput

0.458

High

124606

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

124609

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

124610

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

124612

CUL7
Cullin-7

1

0

High-throughput

0.458

High

124613

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

124616

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

124621

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

124624

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

124626

YAF2
YY1-associated factor 2

1

0

High-throughput

0.458

High

124636

RANB9
Ran-binding protein 9

1

0

High-throughput

0.458

High

124638

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

124640

AKAP9
A-kinase anchor protein 9

1

0

Small-scale

0.458

High

124641

MEP50
Methylosome protein WDR77

1

0

High-throughput

0.458

High

124648

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

124552

PRIO
Major prion protein

1

1

High-throughput

0.445

High

124557

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

124605

E2F1
Transcription factor E2F1

1

1

High-throughput

0.445

High

124607

TAGL
Transgelin

1

2

High-throughput

0.445

High

124589

MLH1
DNA mismatch repair protein Mlh1

1

0

Small-scale

0.438

High

100247

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

124584

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

124611

RBM39
RNA-binding protein 39

1

1

High-throughput

0.437

High

124620

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

124629

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

1

Small-scale

0.437

High

124635

LMTK3
Serine/threonine-protein kinase LMTK3

1

4

High-throughput

0.437

High

124554

IPSP
Plasma serine protease inhibitor

1

0

Small-scale

0.426

High

124590

STAT3
Signal transducer and activator of transcription 3

1

0

High-throughput

0.426

High

124600

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.426

High

124634

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

124643

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

0

High-throughput

0.426

High

124551

ANXA1
Annexin A1

1

2

Small-scale

0.408

High

124595

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

High-throughput

0.408

High

124618

NHSL2
NHS-like protein 2

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024