Interactor 1: MCM3 (P25206)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3)
Gene: MCM3

Interactor 2: MCM7 (Q61881)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog)
Gene: MCM7

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 30108253, 18524952
Identification Methods pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006268 - DNA unwinding involved in DNA replication
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 812
Mm

1 719
+ Hs
+ Xl
+ Mm
+ Hs
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs
+ Xl
+ Hs
+ Xl
+ Xl
+ Xl
+ Dm
+ Xl
+ Dm
+ Dm
+ Ce
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024