HitPredict

Interactor 1: SIS1 (P25294)
Protein SIS1
Gene: SIS1

Interactor 2: MTR4 (P47047)
ATP-dependent RNA helicase DOB1 (EC 3.6.4.13) (mRNA transport regulator MTR4)
Gene: MTR4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	37845327, 19536198
Identification Methods	proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 352 Sc			1 1073
+	Sc
		633348 MAS5_YEAST (1-352): 1.41e-111: 332: 28.13		MTR4_YEAST (1-1073): 0: 819: 100.00
+	Sc
		633118 MAS5_YEAST (1-352): 1.41e-111: 332: 28.13		SKI2_YEAST (2-1073): 0: 584: 32.66
+	Sc
		627907 SIS1_YEAST (1-352): 6.96e-105: 313: 100.00		SKI2_YEAST (2-1073): 0: 584: 32.66
+	Hs
		243495 DNJA2_HUMAN (2-352): 5.07e-121: 356: 28.09		ASCC3_HUMAN (46-735): 4.58e-93: 329: 17.79
+	Sc
		624024 SIS1_YEAST (1-352): 6.96e-105: 313: 100.00		DBP2_YEAST (23-583): 3.84e-93: 309: 11.68
+	Sc
		633433 MAS5_YEAST (1-352): 1.41e-111: 332: 28.13		SLH1_YEAST (128-685): 3.71e-80: 290: 18.70
+	Sc
		633064 MAS5_YEAST (1-352): 1.41e-111: 332: 28.13		BRR2_YEAST (111-872): 7.23e-33: 140: 14.04
+	Hs
		636370 DNJB1_HUMAN (5-352): 5.62e-109: 323: 34.09		DDX60_HUMAN (134-306): 8.62e-11: 68.6: 29.26