Interactor 1: NFS1 (P25374)
Cysteine desulfurase, mitochondrial (EC 2.8.1.7) (tRNA-splicing protein SPL1)
Gene: NFS1

Interactor 2: ISD11 (Q6Q560)
Protein ISD11 (Iron-sulfur protein biogenesis, desulfurase-interacting protein 11)
Gene: ISD11

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 16554755, 16429126, 16341090, 16341089, 19491103, 22813754, 22928949, 29386296, 28941588, 37968396, 32051233, 24045011
Identification Methods affinity chromatography technology, pull down, cross-linking study, blue native page, anti bait coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Aminotran_5~Complex1_LYR
Common GO terms GO:0005739 - mitochondrion
GO:0016226 - iron-sulfur cluster assembly
GO:1990221 - L-cysteine desulfurase complex
GO:1990229 - iron-sulfur cluster assembly complex
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 497
Sc

1 94
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024