HitPredict

Interactor 1: BRD2 (P25440)
Bromodomain-containing protein 2 (O27.1.1)
Gene: BRD2

Interactor 2: PHIP (Q8WWQ0)
PH-interacting protein (PHIP) (DDB1- and CUL4-associated factor 14) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)
Gene: PHIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~Bromodomain
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0070577 - lysine-acetylated histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 801 Hs			1 1821
+	Hs
		1067068 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		PHIP_HUMAN (1-1821): 0: 1502: 100.00
+	Hs
		244704 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		PHIP_HUMAN (1-1821): 0: 1502: 100.00
+	Hs
		164439 TRI66_HUMAN (2-527): 1.93e-51: 197: 16.79		PHIP_HUMAN (1-1821): 0: 1502: 100.00
+	Hs
		631541 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		FBXW7_HUMAN (294-657): 3.51e-56: 211: 17.33
+	Hs
		1016281 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		TBL3_HUMAN (7-495): 2.68e-90: 315: 14.31
+	Hs
		631488 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		244350 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		TBL3_HUMAN (7-495): 2.68e-90: 315: 14.31
+	Hs
		631433 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		TAF5_HUMAN (161-392): 4.53e-18: 92.8: 28.33
+	Hs
		196957 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		PRP4_HUMAN (160-494): 2.06e-16: 86.7: 25.35
+	Hs
		244210 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62
+	Hs
		1067030 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		244901 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		TBL1R_HUMAN (299-580): 2.26e-57: 210: 13.71
+	Hs
		1067111 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		TEP1_HUMAN (4-454): 7.05e-35: 148: 7.87
+	Hs
		244767 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		SNR40_HUMAN (355-666): 5.05e-55: 198: 13.23
+	Hs
		244619 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		1066968 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		TAF5_HUMAN (161-392): 4.53e-18: 92.8: 28.33
+	Hs
		243688 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		TBL1X_HUMAN (423-696): 1.86e-26: 118: 13.03
+	Hs
		1074790 BRDT_HUMAN (48-763): 4.45e-106: 349: 45.39		TAF5_HUMAN (161-392): 4.53e-18: 92.8: 28.33
+	Hs
		196921 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		PRP4_HUMAN (160-494): 2.06e-16: 86.7: 25.35
+	Hs
		243691 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		WDR1_HUMAN (433-682): 6.63e-16: 85.3: 12.22