HitPredict

Interactor 1: PSB3 (P25451)
Proteasome subunit beta type-3 (Macropain subunit PUP3) (Multicatalytic endopeptidase complex subunit PUP3) (Proteasome component PUP3)
Gene: PUP3

Interactor 2: PSB5 (P30656)
Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain subunit PRE2) (Multicatalytic endopeptidase complex subunit PRE2) (Proteasome component PRE2) (Proteinase YSCE subunit PRE2)
Gene: PRE2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.960

The method score is based on:

Property Details
Experiments 11595789, 9087403, 8628401, 16554755, 16429126, 37968396, 22940862
Identification Methods two hybrid, x-ray crystallography, biochemical, affinity chromatography technology, two hybrid array, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0019774 - proteasome core complex, beta-subunit complex
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 205
Sc

1 287
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Last updated: 15 Jul 2024