Interactor 1: SRB8 (P25648)
Mediator of RNA polymerase II transcription subunit 12 (Mediator complex subunit 12) (Suppressor of RNA polymerase B 8)
Gene: SRB8

Interactor 2: MED10 (Q06213)
Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10) (Negative regulator of URS2 protein 2)
Gene: NUT2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 33933450, 37968396
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1427
Sc

1 157
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024