HitPredict

Interactor 1: PSA1 (P25786)
Proteasome subunit alpha type-1 (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain)
Gene: PSMA1

Interactor 2: PSMF1 (Q92530)
Proteasome inhibitor PI31 subunit (hPI31)
Gene: PSMF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005839 - proteasome core complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 263 Hs			1 271
+	Hs
		156330 PSA7_HUMAN (6-234): 9.99e-96: 282: 33.19		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		656281 PSA5_HUMAN (1-236): 5.66e-93: 275: 28.81		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		893716 PSA6_HUMAN (1-240): 1.64e-92: 274: 25.00		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		638170 PSA4_HUMAN (1-233): 4.82e-91: 271: 28.75		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Dm
		522509 PSA1_DROME (1-260): 4.06e-99: 292: 52.42		PSMF1_DROME (3-270): 5e-108: 315: 29.46
+	Hs
		893684 PSA6_HUMAN (1-240): 1.64e-92: 274: 25.00		Q5QPM9_HUMAN (1-183): 1.97e-104: 302: 100.00
+	Dm
		611657 PSA71_DROME (4-233): 2.4e-38: 136: 33.48		PSMF1_DROME (3-270): 5e-108: 315: 29.46