Interactor 1: PSA2 (P25787)
Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3)
Gene: PSMA2

Interactor 2: PSA3 (P25788)
Proteasome subunit alpha type-3 (Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8) (Proteasome component C8)
Gene: PSMA3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 33961781, 35235311, 12376572, 19193609, 15887188, 35271311, 14733938, 9311996
Identification Methods affinity chromatography technology, cross-linking study, biochemical, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome, Proteasome~Proteasome_A_N, Proteasome_A_N~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 234
Hs

1 255
+ Dm
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hv
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Sp
+ Zm
+ Ce
+ Sp
+ Dm
+ Ce
+ Ce

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Last updated: 15 Jul 2024