HitPredict

Interactor 1: PSA2 (P25787)
Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3)
Gene: PSMA2

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	27114451, 12972570
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 234 Hs			1 624
+	Hs
		656327 PSA5_HUMAN (1-233): 2.69e-97: 285: 30.96		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		893768 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		637757 PSA2_HUMAN (1-234): 2.95e-97: 285: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		656337 PSA5_HUMAN (1-233): 2.69e-97: 285: 30.96		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		893771 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Dm
		1278653 PSA5_DROME (1-234): 3.08e-97: 285: 33.88		Q9VWD9_DROME (26-617): 4.15e-130: 395: 44.35
+	Hs
		656323 PSA5_HUMAN (1-233): 2.69e-97: 285: 30.96		UBQL4_HUMAN (22-624): 2.17e-124: 382: 54.55
+	Hs
		893761 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		UBQL4_HUMAN (22-624): 2.17e-124: 382: 54.55
+	Hs
		637721 PSA2_HUMAN (1-234): 2.95e-97: 285: 100.00		DDI1_HUMAN (43-314): 2.92e-54: 191: 15.60
+	Hs
		656280 PSA5_HUMAN (1-233): 2.69e-97: 285: 30.96		DDI1_HUMAN (43-314): 2.92e-54: 191: 15.60
+	Hs
		637701 PSA2_HUMAN (1-234): 2.95e-97: 285: 100.00		DDI2_HUMAN (43-314): 6.26e-52: 185: 14.59
+	Hs
		656249 PSA5_HUMAN (1-233): 2.69e-97: 285: 30.96		DDI2_HUMAN (43-314): 6.26e-52: 185: 14.59
+	Hs
		893715 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		DDI1_HUMAN (43-314): 2.92e-54: 191: 15.60
+	Hs
		893686 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		DDI2_HUMAN (43-314): 6.26e-52: 185: 14.59
+	Zm
		59016 A3FMB9_MAIZE (4-230): 4.78e-91: 269: 41.30		K7UR93_MAIZE (33-313): 1.02e-39: 152: 14.39
+	Hs
		656197 PSA5_HUMAN (1-233): 2.69e-97: 285: 30.96		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		893646 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		637386 PSA1_HUMAN (1-233): 1.31e-89: 266: 30.67		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		893645 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		637385 PSA1_HUMAN (1-233): 1.31e-89: 266: 30.67		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27