Interactor 1: ISY1 (P21374)
Pre-mRNA-splicing factor ISY1 (Interactor of SYF1) (PRP19-associated complex protein 30)
Gene: ISY1

Interactor 2: PRP17 (P40968)
Pre-mRNA-processing factor 17 (Cell division control protein 40)
Gene: CDC40

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 37968396
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Isy1~WD40
Common GO terms GO:0000350 - generation of catalytic spliceosome for second transesterification step
GO:0000389 - mRNA 3'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0071013 - catalytic step 2 spliceosome
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 235
Sc

1 455
+ Sp
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025