HitPredict

Interactor 1: BTG4 (O70552)
Protein BTG4 (BTG family member 4) (Protein PC3b)
Gene: BTG4

Interactor 2: CNOT7 (Q60809)
CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (CCR4-associated factor 1) (CAF-1)
Gene: CNOT7

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	27065194
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BTG~CAF1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008285 - negative regulation of cell population proliferation
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 250 Mm			1 285
+	Mm
		251046 BTG4_MOUSE (1-250): 1.49e-153: 428: 100.00		CNOT8_MOUSE (1-282): 2.91e-175: 486: 76.60
+	Hs
		1051207 BTG3_HUMAN (1-231): 6.93e-113: 325: 42.00		CNOT7_HUMAN (1-285): 0: 507: 99.65
+	Hs
		1051204 BTG3_HUMAN (1-231): 6.93e-113: 325: 42.00		CNOT8_HUMAN (1-282): 1.21e-175: 487: 76.60
+	Hs
		841404 TOB1_HUMAN (1-135): 9.17e-53: 176: 32.85		CNOT7_HUMAN (1-285): 0: 507: 99.65
+	Hs
		944599 BTG2_HUMAN (1-107): 1.29e-49: 161: 42.20		CNOT7_HUMAN (1-285): 0: 507: 99.65
+	Hs
		1152299 Q6IBC8_HUMAN (1-107): 8.18e-49: 160: 41.28		CNOT7_HUMAN (1-285): 0: 507: 99.65
+	Hs
		912794 BTG1_HUMAN (1-107): 8.18e-49: 160: 41.28		CNOT7_HUMAN (1-285): 0: 507: 99.65
+	Mm
		912801 BTG1_MOUSE (1-107): 8.18e-49: 160: 41.28		CNOT7_MOUSE (1-285): 0: 507: 100.00
+	Hs
		1048317 TOB2_HUMAN (1-108): 1.44e-46: 159: 36.36		CNOT7_HUMAN (1-285): 0: 507: 99.65
+	Mm
		978994 BTG2_MOUSE (1-107): 8.6e-48: 157: 40.37		CNOT7_MOUSE (1-285): 0: 507: 100.00
+	Hs
		841403 TOB1_HUMAN (1-135): 9.17e-53: 176: 32.85		CNOT8_HUMAN (1-282): 1.21e-175: 487: 76.60
+	Hs
		944598 BTG2_HUMAN (1-107): 1.29e-49: 161: 42.20		CNOT8_HUMAN (1-282): 1.21e-175: 487: 76.60
+	Hs
		1152298 Q6IBC8_HUMAN (1-107): 8.18e-49: 160: 41.28		CNOT8_HUMAN (1-282): 1.21e-175: 487: 76.60
+	Hs
		912793 BTG1_HUMAN (1-107): 8.18e-49: 160: 41.28		CNOT8_HUMAN (1-282): 1.21e-175: 487: 76.60
+	Hs
		1048316 TOB2_HUMAN (1-108): 1.44e-46: 159: 36.36		CNOT8_HUMAN (1-282): 1.21e-175: 487: 76.60
+	Mm
		912802 BTG1_MOUSE (1-107): 8.18e-49: 160: 41.28		CNOT8_MOUSE (1-282): 2.91e-175: 486: 76.60
+	Mm
		978995 BTG2_MOUSE (1-107): 8.6e-48: 157: 40.37		CNOT8_MOUSE (1-282): 2.91e-175: 486: 76.60
+	Dm
		1155377 Q6NQY2_DROME (1-136): 8.46e-46: 162: 33.33		Q9VTS4_DROME (2-273): 8.58e-159: 445: 72.26
+	Dm
		60235 A4V4L0_DROME (1-135): 3.35e-46: 162: 32.12		X2JCC3_DROME (2-256): 1.59e-146: 417: 68.87