HitPredict

Interactor 1: PSA4 (P25789)
Proteasome subunit alpha type-4 (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome component C9) (Proteasome subunit L)
Gene: PSMA4

Interactor 2: POMP (Q9Y244)
Proteasome maturation protein (Proteassemblin) (Protein UMP1 homolog) (hUMP1) (Voltage-gated K channel beta subunit 4.1)
Gene: POMP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.806

Property	Details
Experiments	33961781, 17948026
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Proteasome~UMP1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 141
+	Hs
		893773 PSA6_HUMAN (2-244): 3.23e-92: 273: 31.84		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		637608 PSA1_HUMAN (4-259): 2.5e-91: 272: 28.57		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		156378 PSA7_HUMAN (5-238): 2.84e-91: 271: 33.19		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Dm
		574038 PSA4_DROME (1-242): 9.91e-93: 275: 72.25		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1278643 PSA5_DROME (3-241): 6.79e-89: 265: 32.11		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1367998 PSA6_DROME (2-244): 2.34e-86: 258: 29.10		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Hs
		637759 PSA2_HUMAN (3-214): 6.04e-42: 145: 38.68		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Dm
		771316 PSA2_DROME (2-221): 4.75e-44: 150: 39.64		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50