Protein: LPAR2
Lysophosphatidic acid receptor 2 (LPA receptor 2) (LPA-2) (Lysophosphatidic acid receptor Edg-4)

Gene: LPAR2
Organism: Homo sapiens
Interactions: 119
UniProt ID: Q9HBW0

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

709282

AA2BR
Adenosine receptor A2b

1

17

High-throughput

0.691

High

1151659

TRIP6
Thyroid receptor-interacting protein 6

3

2

Small-scale

0.674

High

1150490

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

3

20

Small-scale

0.667

High

609810

LEG3
Galectin-3

2

6

High-throughput

0.628

High

1438456

SEC12
Guanine nucleotide-exchange factor SEC12

1

3

High-throughput

0.618

High

1246436

CORO6
Coronin-6

1

0

High-throughput

0.578

High

186271

SIVA
Apoptosis regulatory protein Siva

1

1

Small-scale

0.561

High

564392

CFTR
Cystic fibrosis transmembrane conductance regulator

1

11

Small-scale

0.554

High

927558

ATX1
Ataxin-1

1

1

High-throughput

0.541

High

1034131

PLCB3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

1

0

Small-scale

0.537

High

125618

LEG9
Galectin-9

1

6

High-throughput

0.536

High

164963

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

6

High-throughput

0.536

High

178401

NPC1
NPC intracellular cholesterol transporter 1

1

10

High-throughput

0.536

High

181439

PGRC2
Membrane-associated progesterone receptor component 2

1

4

High-throughput

0.536

High

184515

SURF4
Surfeit locus protein 4

1

1

High-throughput

0.536

High

270688

ATP9A
Probable phospholipid-transporting ATPase IIA

1

4

High-throughput

0.536

High

297272

PRAF3
PRA1 family protein 3

1

6

High-throughput

0.536

High

349578

TSN15
Tetraspanin-15

1

20

High-throughput

0.536

High

420049

B3A2
Anion exchange protein 2

1

2

High-throughput

0.536

High

506993

POTEI
POTE ankyrin domain family member I

1

8

High-throughput

0.536

High

560527

IFM1
Interferon-induced transmembrane protein 1

1

2

High-throughput

0.536

High

611361

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

7

High-throughput

0.536

High

720047

HMOX2
Heme oxygenase 2

1

5

High-throughput

0.536

High

857565

NOTC1
Neurogenic locus notch homolog protein 1

1

1

High-throughput

0.536

High

1023395

AT2C1
Calcium-transporting ATPase type 2C member 1

1

20

High-throughput

0.536

High

1064730

CD47
Leukocyte surface antigen CD47

1

3

High-throughput

0.536

High

1105245

S39A6
Zinc transporter ZIP6

1

20

High-throughput

0.536

High

1147854

DHC24
Delta(24)-sterol reductase

1

2

High-throughput

0.536

High

1154078

MSMO1
Methylsterol monooxygenase 1

1

7

High-throughput

0.536

High

1212304

TM63B
Mechanosensitive cation channel TMEM63B

1

2

High-throughput

0.536

High

1232915

IPIL1
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1

1

4

High-throughput

0.536

High

1240963

S27A4
Long-chain fatty acid transport protein 4

1

3

High-throughput

0.536

High

1242464

CNNM4
Metal transporter CNNM4

1

5

High-throughput

0.536

High

1242939

S39A4
Zinc transporter ZIP4

1

20

High-throughput

0.536

High

1243665

S27A1
Long-chain fatty acid transport protein 1

1

3

High-throughput

0.536

High

1278323

LRP10
Low-density lipoprotein receptor-related protein 10

1

1

High-throughput

0.536

High

1290222

GP180
Integral membrane protein GPR180

1

5

High-throughput

0.536

High

1292582

PAQR7
Membrane progestin receptor alpha

1

3

High-throughput

0.536

High

1307645

ZDH17
Palmitoyltransferase ZDHHC17

1

11

High-throughput

0.536

High

1335573

DGLB
Diacylglycerol lipase-beta

1

4

High-throughput

0.536

High

1337961

ZNT7
Zinc transporter 7

1

14

High-throughput

0.536

High

1349336

TBC15
TBC1 domain family member 15

1

9

High-throughput

0.536

High

1401706

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

9

High-throughput

0.536

High

1410319

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

5

High-throughput

0.536

High

1421253

TTYH3
Protein tweety homolog 3

1

11

High-throughput

0.536

High

1428161

YIPF3
Protein YIPF3

1

6

High-throughput

0.536

High

1429430

T126A
Transmembrane protein 126A

1

5

High-throughput

0.536

High

1429746

ADT4
ADP/ATP translocase 4

1

12

High-throughput

0.536

High

1438459

GPC5C
G-protein coupled receptor family C group 5 member C

1

13

High-throughput

0.536

High

1438460

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

3

High-throughput

0.536

High

1438463

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

6

High-throughput

0.536

High

1438467

S39AA
Zinc transporter ZIP10

1

20

High-throughput

0.536

High

1438469

TMCO1
Calcium load-activated calcium channel

1

3

High-throughput

0.536

High

749400

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.513

High

1159237

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.513

High

1438473

SKAP
Small kinetochore-associated protein

1

0

High-throughput

0.513

High

167653

GIPC1
PDZ domain-containing protein GIPC1

1

2

Small-scale

0.501

High

167005

MGST3
Glutathione S-transferase 3, mitochondrial

1

3

High-throughput

0.489

High

178987

SCAM2
Secretory carrier-associated membrane protein 2

1

9

High-throughput

0.489

High

185037

SPTC2
Serine palmitoyltransferase 2

1

4

High-throughput

0.489

High

193721

TPSN
Tapasin

1

3

High-throughput

0.489

High

219374

B4GA1
Beta-1,4-glucuronyltransferase 1

1

3

High-throughput

0.489

High

225390

ERD23
ER lumen protein-retaining receptor 3

1

7

High-throughput

0.489

High

270055

XYLK
Glycosaminoglycan xylosylkinase

1

2

High-throughput

0.489

High

290986

PPM1B
Protein phosphatase 1B

1

1

High-throughput

0.489

High

344493

STR3N
STARD3 N-terminal-like protein

1

3

High-throughput

0.489

High

399738

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

1

10

High-throughput

0.489

High

536293

PPAL
Lysosomal acid phosphatase

1

6

High-throughput

0.489

High

690725

AOFB
Amine oxidase [flavin-containing] B

1

2

High-throughput

0.489

High

702041

TMOD1
Tropomodulin-1

1

1

High-throughput

0.489

High

789964

FDFT
Squalene synthase

1

3

High-throughput

0.489

High

832805

BCL6
B-cell lymphoma 6 protein

1

1

Small-scale

0.489

High

1043180

TAP1
Antigen peptide transporter 1

1

9

High-throughput

0.489

High

1053841

KDSR
3-ketodihydrosphingosine reductase

1

16

High-throughput

0.489

High

1083207

GALT1
Polypeptide N-acetylgalactosaminyltransferase 1

1

1

High-throughput

0.489

High

1085387

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

10

High-throughput

0.489

High

1187378

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

1

9

High-throughput

0.489

High

1203396

YIF1B
Protein YIF1B

1

3

High-throughput

0.489

High

1204594

PIGG
GPI ethanolamine phosphate transferase 2, catalytic subunit

1

10

High-throughput

0.489

High

1231803

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

1

1

High-throughput

0.489

High

1251753

CERS6
Ceramide synthase 6

1

14

High-throughput

0.489

High

1275409

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

5

High-throughput

0.489

High

1280078

FRMD5
FERM domain-containing protein 5

1

5

High-throughput

0.489

High

1315485

K2013
Uncharacterized protein KIAA2013

1

6

High-throughput

0.489

High

1348328

GOGA5
Golgin subfamily A member 5

1

4

High-throughput

0.489

High

1352522

GPX8
Probable glutathione peroxidase 8

1

2

High-throughput

0.489

High

1357333

THEM6
Protein THEM6

1

3

High-throughput

0.489

High

1372395

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

20

High-throughput

0.489

High

1382725

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

3

High-throughput

0.489

High

1383477

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

3

High-throughput

0.489

High

1386931

F241B
Protein FAM241B

1

6

High-throughput

0.489

High

1388803

YIPF6
Protein YIPF6

1

6

High-throughput

0.489

High

1389598

SAAL1
Protein SAAL1

1

3

High-throughput

0.489

High

1389726

TV23C
Golgi apparatus membrane protein TVP23 homolog C

1

2

High-throughput

0.489

High

1399174

VMA22
Vacuolar ATPase assembly protein VMA22

1

1

High-throughput

0.489

High

1404219

SEC62
Translocation protein SEC62

1

2

High-throughput

0.489

High

1415275

PTSS2
Phosphatidylserine synthase 2

1

7

High-throughput

0.489

High

1418035

FUT8
Alpha-(1,6)-fucosyltransferase

1

3

High-throughput

0.489

High

1421141

LNP
Endoplasmic reticulum junction formation protein lunapark

1

2

High-throughput

0.489

High

1428306

DERL2
Derlin-2

1

3

High-throughput

0.489

High

1430881

METL9
Protein-L-histidine N-pros-methyltransferase

1

1

High-throughput

0.489

High

1438457

AT131
Endoplasmic reticulum transmembrane helix translocase

1

20

High-throughput

0.489

High

1438458

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

1

High-throughput

0.489

High

1438461

RMND1
Required for meiotic nuclear division protein 1 homolog

1

3

High-throughput

0.489

High

1438462

TM160
Transmembrane protein 160

1

3

High-throughput

0.489

High

1438464

CNIH4
Protein cornichon homolog 4

1

2

High-throughput

0.489

High

1438465

SEC63
Translocation protein SEC63 homolog

1

2

High-throughput

0.489

High

1438466

RAB21
Ras-related protein Rab-21

1

9

High-throughput

0.489

High

1438468

TPC1
Two pore channel protein 1

1

6

High-throughput

0.489

High

1438470

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

9

High-throughput

0.489

High

1438472

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

5

High-throughput

0.489

High

1438474

FADS3
Fatty acid desaturase 3

1

5

High-throughput

0.489

High

1438475

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

6

High-throughput

0.489

High

814869

CUX1
Homeobox protein cut-like 1

1

1

High-throughput

0.437

High

1119460

CASP
Protein CASP

1

1

High-throughput

0.407

High

999409

HBB
Hemoglobin subunit beta

2

0

High-throughput

0.328

High

161255

EI24
Etoposide-induced protein 2.4 homolog

1

0

High-throughput

0.279

Low

1213707

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.279

Low

1438471

PIGL
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025