HitPredict

Interactor 1: RBTN2 (P25791)
Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2)
Gene: LMO2

Interactor 2: SSBP2 (P81877)
Single-stranded DNA-binding protein 2 (Sequence-specific single-stranded-DNA-binding protein 2)
Gene: SSBP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 17437998
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 158 Hs			1 361
+	Hs
		946646 LHX8_HUMAN (24-148): 1.1e-47: 159: 33.60		SSBP2_HUMAN (1-361): 6.02e-60: 198: 100.00
+	Mm
		1321867 ISL2_MOUSE (12-148): 2.2e-41: 143: 32.61		SSBP2_MOUSE (1-361): 8.29e-60: 198: 99.72
+	Hs
		946656 ISL2_HUMAN (12-148): 1.24e-41: 143: 32.61		SSBP2_HUMAN (1-361): 6.02e-60: 198: 100.00
+	Hs
		899917 ISL1_HUMAN (22-148): 6.29e-41: 141: 34.38		SSBP2_HUMAN (1-361): 6.02e-60: 198: 100.00
+	Mm
		899943 ISL1_MOUSE (22-148): 6.29e-41: 141: 34.38		SSBP2_MOUSE (1-361): 8.29e-60: 198: 99.72
+	Hs
		1148490 LHX8_HUMAN (24-148): 1.1e-47: 159: 33.60		SSBP4_HUMAN (1-361): 2.16e-51: 177: 68.73
+	Hs
		1148491 LHX8_HUMAN (24-148): 1.1e-47: 159: 33.60		SSBP3_HUMAN (5-361): 4.06e-51: 176: 74.16
+	Hs
		946674 LHX6_HUMAN (7-153): 2.16e-38: 135: 27.70		SSBP2_HUMAN (1-361): 6.02e-60: 198: 100.00
+	Mm
		1112383 ISL2_MOUSE (12-148): 2.2e-41: 143: 32.61		Q3U4B1_MOUSE (5-361): 1.77e-52: 179: 70.72
+	Hs
		1283495 ISL2_HUMAN (12-148): 1.24e-41: 143: 32.61		SSBP4_HUMAN (1-361): 2.16e-51: 177: 68.73
+	Hs
		1283496 ISL2_HUMAN (12-148): 1.24e-41: 143: 32.61		SSBP3_HUMAN (5-361): 4.06e-51: 176: 74.16
+	Mm
		1321868 ISL2_MOUSE (12-148): 2.2e-41: 143: 32.61		SSBP3_MOUSE (5-361): 4.06e-51: 176: 74.16
+	Hs
		899932 ISL1_HUMAN (22-148): 6.29e-41: 141: 34.38		SSBP4_HUMAN (1-361): 2.16e-51: 177: 68.73
+	Hs
		110821 H7C0H1_HUMAN (7-151): 3.5e-40: 141: 32.03		SSBP3_HUMAN (5-361): 4.06e-51: 176: 74.16
+	Hs
		899933 ISL1_HUMAN (22-148): 6.29e-41: 141: 34.38		SSBP3_HUMAN (5-361): 4.06e-51: 176: 74.16
+	Mm
		899944 ISL1_MOUSE (22-148): 6.29e-41: 141: 34.38		SSBP3_MOUSE (5-361): 4.06e-51: 176: 74.16
+	Hs
		638386 RBTN2_HUMAN (1-158): 4.5e-41: 136: 100.00		SSBP4_HUMAN (1-361): 2.16e-51: 177: 68.73
+	Hs
		1314660 LHX6_HUMAN (7-153): 2.16e-38: 135: 27.70		SSBP4_HUMAN (1-361): 2.16e-51: 177: 68.73
+	Hs
		638387 RBTN2_HUMAN (1-158): 4.5e-41: 136: 100.00		SSBP3_HUMAN (5-361): 4.06e-51: 176: 74.16
+	Dm
		284838 O77284_DROME (26-151): 1.52e-39: 137: 55.56		Q9VEB9_DROME (5-333): 1.74e-31: 125: 38.73