Protein: TMCO1
Calcium load-activated calcium channel (CLAC channel) (GEL complex subunit TMCO1) (Transmembrane and coiled-coil domain-containing protein 1) (Transmembrane and coiled-coil domains protein 4) (Xenogeneic cross-immune protein PCIA3)

Gene: TMCO1
Organism: Homo sapiens
Interactions: 178
UniProt ID: Q9UM00

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001503 - ossification
GO:0005262 - calcium channel activity
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1414748

RCAF1
GEL complex subunit OPTI

1

0

High-throughput

0.656

High

1453745

EMC3
ER membrane protein complex subunit 3

1

0

High-throughput

0.656

High

1382242

CCD47
PAT complex subunit CCDC47

3

0

Small-scale

0.628

High

1381365

NCLN
BOS complex subunit NCLN

2

0

Small-scale

0.585

High

1461885

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.578

High

397209

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

988823

RAC1
Ras-related C3 botulinum toxin substrate 1

2

3

High-throughput

0.571

High

951518

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

1461258

AMFR
E3 ubiquitin-protein ligase AMFR

1

0

Small-scale

0.537

High

351987

S1PR4
Sphingosine 1-phosphate receptor 4

1

3

High-throughput

0.536

High

638261

S1PR1
Sphingosine 1-phosphate receptor 1

1

2

High-throughput

0.536

High

638552

FPR1
fMet-Leu-Phe receptor

1

6

High-throughput

0.536

High

669084

FPR2
N-formyl peptide receptor 2

1

6

High-throughput

0.536

High

1372418

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

1

High-throughput

0.536

High

1380498

YIPF5
Protein YIPF5

1

1

High-throughput

0.536

High

1438469

LPAR2
Lysophosphatidic acid receptor 2

1

3

High-throughput

0.536

High

820773

CEAM6
Cell adhesion molecule CEACAM6

1

0

High-throughput

0.517

High

1453547

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.517

High

1431007

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.515

High

130284

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.513

High

530570

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

538712

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

0

High-throughput

0.513

High

699252

CALX
Calnexin

1

0

High-throughput

0.513

High

889038

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.513

High

890073

PSN1
Presenilin-1

1

0

High-throughput

0.513

High

927171

ATX3
Ataxin-3

1

0

High-throughput

0.513

High

958049

RAB14
Ras-related protein Rab-14

1

0

High-throughput

0.513

High

1034848

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

1086141

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.513

High

1141033

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.513

High

1161259

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.513

High

1310520

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1324885

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

1350101

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

1384636

S67A1
Solute carrier family 67 member A1

1

0

High-throughput

0.513

High

1413412

RBM42
RNA-binding protein 42

1

0

High-throughput

0.513

High

1451421

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.513

High

1453842

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.513

High

1461883

A4GCT
Alpha-1,4-N-acetylglucosaminyltransferase

1

0

High-throughput

0.513

High

1461887

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.513

High

1405225

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.493

High

166072

FFAR1
Free fatty acid receptor 1

1

6

High-throughput

0.489

High

182831

GP182
G-protein coupled receptor 182

1

5

High-throughput

0.489

High

231819

MFS11
UNC93-like protein MFSD11

1

1

High-throughput

0.489

High

320513

TM63A
Mechanosensitive cation channel TMEM63A

1

1

High-throughput

0.489

High

771267

APJ
Apelin receptor

1

3

High-throughput

0.489

High

833887

P2RY2
P2Y purinoceptor 2

1

6

High-throughput

0.489

High

907072

CCR6
C-C chemokine receptor type 6

1

2

High-throughput

0.489

High

936139

PAR2
Proteinase-activated receptor 2

1

5

High-throughput

0.489

High

1101707

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

5

High-throughput

0.489

High

1212322

TM63B
Mechanosensitive cation channel TMEM63B

1

1

High-throughput

0.489

High

1242972

S39A4
Zinc transporter ZIP4

1

1

High-throughput

0.489

High

1291920

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

6

High-throughput

0.489

High

1407316

CML1
Chemerin-like receptor 1

1

6

High-throughput

0.489

High

1438773

GPR35
G-protein coupled receptor 35

1

4

High-throughput

0.489

High

174147

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.479

High

374280

RASN
GTPase NRas

1

2

High-throughput

0.479

High

376092

RASK
GTPase KRas

1

3

High-throughput

0.479

High

466525

RHOC
Rho-related GTP-binding protein RhoC

1

4

High-throughput

0.479

High

901676

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.479

High

920359

PLK1
Serine/threonine-protein kinase PLK1

1

2

High-throughput

0.479

High

955751

CDC42
Cell division control protein 42 homolog

1

3

High-throughput

0.479

High

962629

RHOA
Transforming protein RhoA

1

4

High-throughput

0.479

High

999564

NOMO3
BOS complex subunit NOMO3

1

1

Small-scale

0.479

High

1058724

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.479

High

1143699

NOMO1
BOS complex subunit NOMO1

1

1

Small-scale

0.479

High

1163882

DUS6
Dual specificity protein phosphatase 6

1

1

High-throughput

0.479

High

1331155

CE112
Centrosomal protein of 112 kDa

1

1

High-throughput

0.479

High

1392499

TECT2
Tectonic-2

1

1

High-throughput

0.479

High

1448925

DUS22
Dual specificity protein phosphatase 22

1

1

High-throughput

0.479

High

178440

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

294524

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

320140

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

346492

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

418512

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

468911

HS90B
Heat shock protein HSP 90-beta

1

0

High-throughput

0.458

High

611417

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

616046

RL17
Large ribosomal subunit protein uL22

1

0

Small-scale

0.458

High

630664

RAB3B
Ras-related protein Rab-3B

1

0

High-throughput

0.458

High

715843

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

822907

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

831640

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

846806

GRK6
G protein-coupled receptor kinase 6

1

0

High-throughput

0.458

High

847747

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

888389

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

904198

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

930381

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

0

High-throughput

0.458

High

947312

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

963149

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

0

Small-scale

0.458

High

1005242

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1111747

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

1136702

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.458

High

1218694

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.458

High

1249322

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1256077

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1334061

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.458

High

1335061

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1393819

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1395634

RN170
E3 ubiquitin-protein ligase RNF170

1

0

High-throughput

0.458

High

1397549

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1401256

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1401955

ERBIN
Erbin

1

0

High-throughput

0.458

High

1404280

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1412719

ESYT1
Extended synaptotagmin-1

1

0

High-throughput

0.458

High

1414504

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1415454

TM147
BOS complex subunit TMEM147

1

0

Small-scale

0.458

High

1417854

RNF26
E3 ubiquitin-protein ligase RNF26

1

0

High-throughput

0.458

High

1435447

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1436363

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1438555

LFG4
Protein lifeguard 4

1

0

High-throughput

0.458

High

1448041

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1448319

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

1450136

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

1452725

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

1454860

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

1459299

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1461888

RBM8A
RNA-binding protein 8A

1

0

High-throughput

0.458

High

170428

AURKA
Aurora kinase A

1

1

High-throughput

0.437

High

189922

STX7
Syntaxin-7

1

5

High-throughput

0.437

High

562485

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.437

High

978402

RHOB
Rho-related GTP-binding protein RhoB

1

4

High-throughput

0.437

High

1081692

K2012
Uncharacterized protein KIAA2012

1

1

High-throughput

0.437

High

1087340

STX4
Syntaxin-4

1

6

High-throughput

0.437

High

1238852

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1367579

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

1391850

AURKB
Aurora kinase B

1

1

High-throughput

0.437

High

1396656

RHOV
Rho-related GTP-binding protein RhoV

1

3

High-throughput

0.437

High

1461884

LAMP3
Lysosome-associated membrane glycoprotein 3

1

1

High-throughput

0.437

High

1209791

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

722662

CTR1
High affinity cationic amino acid transporter 1

1

3

High-throughput

0.407

High

912727

CTR2
Cationic amino acid transporter 2

1

3

High-throughput

0.407

High

1139603

S39AE
Metal cation symporter ZIP14

1

1

High-throughput

0.407

High

1348659

S7A14
Solute carrier family 7 member 14

1

3

High-throughput

0.407

High

1361330

CTR3
Cationic amino acid transporter 3

1

3

High-throughput

0.407

High

226382

SNG1
Synaptogyrin-1

1

0

High-throughput

0.279

Low

260986

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

469570

SYPH
Synaptophysin

1

0

High-throughput

0.279

Low

519679

LYAG
Lysosomal alpha-glucosidase

1

0

High-throughput

0.279

Low

733097

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

0

High-throughput

0.279

Low

845157

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.279

Low

867512

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

883731

CENPA
Histone H3-like centromeric protein A

1

0

High-throughput

0.279

Low

1251699

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

1350914

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1387686

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

1399644

OPALI
Opalin

1

0

High-throughput

0.279

Low

1452228

CLDN1
Claudin domain-containing protein 1

1

0

High-throughput

0.279

Low

67203

F177B
Protein FAM177B

1

0

High-throughput

0.269

Low

1041620

KMT2A
Histone-lysine N-methyltransferase 2A

1

0

High-throughput

0.269

Low

1339896

KNL1
Outer kinetochore KNL1 complex subunit KNL1

1

0

High-throughput

0.269

Low

1277670

K1C26
Keratin, type I cytoskeletal 26

1

0

High-throughput

0.268

Low

124664

EYA2
Protein phosphatase EYA2

1

0

High-throughput

0.249

Low

155716

CUX2
Homeobox protein cut-like 2

1

0

High-throughput

0.249

Low

157980

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

377233

SOMA
Somatotropin

1

0

High-throughput

0.249

Low

590022

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696854

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

769502

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

901104

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.249

Low

937967

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.249

Low

971283

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

1081728

CF210
Cilia- and flagella- associated protein 210

1

0

High-throughput

0.249

Low

1100534

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.249

Low

1126207

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

1201969

BRDT
Bromodomain testis-specific protein

1

0

High-throughput

0.249

Low

1229763

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1323042

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low

1339231

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.249

Low

1356657

IASPP
RelA-associated inhibitor

1

0

Small-scale

0.249

Low

1383279

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.249

Low

1448179

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

1449990

T106B
Transmembrane protein 106B

1

0

High-throughput

0.249

Low

1461882

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.249

Low

1461886

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.249

Low

430498

JUN
Transcription factor Jun

1

0

High-throughput

0.232

Low

1236377

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.232

Low

1309007

S22A9
Organic anion transporter 7

1

0

High-throughput

0.232

Low

1357838

S35F5
Solute carrier family 35 member F5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025