HitPredict

Interactor 1: SYT1 (P21579)
Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)
Gene: SYT1

Interactor 2: STX3 (Q13277)
Syntaxin-3
Gene: STX3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	10397765
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C2~SNARE, C2~Syntaxin
Common GO terms	GO:0000149 - SNARE binding GO:0005886 - plasma membrane GO:0006906 - vesicle fusion GO:0043005 - neuron projection GO:0048278 - vesicle docking and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 422 Hs			1 289
+	Hs
		639106 SYT1_HUMAN (1-422): 8.89e-129: 379: 100.00		STX2_HUMAN (1-287): 3.92e-77: 238: 63.45
+	Hs
		639135 SYT1_HUMAN (1-422): 8.89e-129: 379: 100.00		STX1A_HUMAN (1-286): 4.51e-75: 233: 62.98
+	Rn
		639904 SYT1_RAT (1-422): 3.16e-125: 370: 97.87		STX1A_RAT (1-287): 4.87e-77: 238: 63.45
+	Hs
		639124 SYT1_HUMAN (1-422): 8.89e-129: 379: 100.00		STX4_HUMAN (1-286): 8.44e-62: 199: 39.32
+	Mm
		204919 SYT2_MOUSE (2-422): 1.25e-113: 340: 74.18		STX1A_MOUSE (1-287): 5.49e-77: 237: 63.45
+	Dm
		638694 SY65_DROME (7-422): 1.66e-110: 334: 57.42		STX1A_DROME (2-284): 1.94e-73: 228: 55.59
+	Dm
		1174531 Q9U6P7_DROME (13-410): 2.91e-87: 275: 29.41		STX1A_DROME (2-284): 1.94e-73: 228: 55.59
+	Rn
		746105 RP3A_RAT (21-286): 2.57e-40: 154: 23.86		STX1A_RAT (1-287): 4.87e-77: 238: 63.45