HitPredict

Interactor 1: PROF (P25843)
Profilin (Protein chickadee)
Gene: chic

Interactor 2: Q8IRY0 (Q8IRY0)
Dishevelled associated activator of morphogenesis, isoform B (Dishevelled associated activator of morphogenesis, isoform E) (Dishevelled associated activator of morphogenesis, isoform F) (Dishevelled associated activator of morphogenesis, isoform G)
Gene: DAAM

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19052223
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030041 - actin filament polymerization GO:0051491 - positive regulation of filopodium assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Dm			1 1153
+	Hs
		430352 PROF1_HUMAN (3-126): 1.89e-38: 128: 20.71		DIAP3_HUMAN (27-1125): 0: 718: 23.00
+	Dm
		639180 PROF_DROME (1-126): 5.22e-54: 167: 100.00		DIA_DROME (31-1129): 0: 646: 22.72
+	Hs
		237549 PROF1_HUMAN (3-126): 1.89e-38: 128: 20.71		DIAP1_HUMAN (15-1116): 0: 683: 21.54
+	Hs
		237564 PROF2_HUMAN (3-126): 1.79e-33: 115: 20.71		DIAP1_HUMAN (15-1116): 0: 683: 21.54
+	Hs
		430307 PROF1_HUMAN (3-126): 1.89e-38: 128: 20.71		FMNL2_HUMAN (15-1123): 0: 656: 18.92
+	Dd
		640684 PROF2_DICDI (1-123): 8.25e-42: 136: 39.02		FORH_DICDI (25-1064): 0: 595: 21.26
+	Hs
		314830 PROF1_HUMAN (3-126): 1.89e-38: 128: 20.71		FMNL1_HUMAN (40-1125): 0: 581: 18.61
+	Hs
		314847 PROF2_HUMAN (3-126): 1.79e-33: 115: 20.71		FMNL1_HUMAN (40-1125): 0: 581: 18.61
+	Hs
		430404 PROF1_HUMAN (3-126): 1.89e-38: 128: 20.71		FHOD1_HUMAN (113-1142): 3.84e-177: 553: 14.13
+	Hs
		715022 PROF2_HUMAN (3-126): 1.79e-33: 115: 20.71		FHOD1_HUMAN (113-1142): 3.84e-177: 553: 14.13
+	Hs
		430197 PROF1_HUMAN (3-126): 1.89e-38: 128: 20.71		INF2_HUMAN (108-1137): 1.6e-169: 536: 22.25
+	Hs
		714970 PROF2_HUMAN (3-126): 1.79e-33: 115: 20.71		INF2_HUMAN (108-1137): 1.6e-169: 536: 22.25
+	Ce
		109520 PROF1_CAEEL (1-126): 2.81e-38: 127: 27.27		H2KYI3_CAEEL (42-1143): 4.63e-158: 509: 18.62
+	At
		221287 PRF3_ARATH (1-125): 3.06e-57: 176: 40.77		FH4_ARATH (624-1045): 1.77e-101: 340: 20.43
+	Hs
		243087 PROF1_HUMAN (3-126): 1.89e-38: 128: 20.71		DIAP2_HUMAN (634-1128): 5.09e-116: 388: 25.76
+	At
		221286 PRF2_ARATH (1-125): 2.04e-54: 168: 40.77		FH4_ARATH (624-1045): 1.77e-101: 340: 20.43
+	Hs
		430356 PROF1_HUMAN (3-126): 1.89e-38: 128: 20.71		FMN2_HUMAN (593-1066): 2.83e-98: 346: 22.89
+	Dm
		639185 PROF_DROME (1-126): 5.22e-54: 167: 100.00		CAPU_DROME (605-1070): 2.47e-85: 302: 20.27
+	Sc
		425514 PROF_YEAST (1-126): 4.75e-47: 149: 39.37		BNR1_YEAST (602-1086): 4.28e-84: 302: 20.59
+	Sp
		764559 PROF_SCHPO (1-126): 2.53e-49: 155: 37.01		CDC12_SCHPO (26-535): 3.13e-24: 112: 14.71