HitPredict

Interactor 1: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Interactor 2: COMD1 (Q8N668)
COMM domain-containing protein 1 (Protein Murr1)
Gene: COMMD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	25520503, 14685242, 20068069, 16573520
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032088 - negative regulation of NF-kappaB transcription factor activity
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 190
+	Hs
		961406 NFKB2_HUMAN (68-294): 6.66e-64: 218: 34.32		COMD1_HUMAN (1-190): 1.69e-127: 357: 100.00
+	Hs
		587632 NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35		COMD1_HUMAN (1-190): 1.69e-127: 357: 100.00