HitPredict

Interactor 1: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Interactor 2: ASB2 (Q96Q27)
Ankyrin repeat and SOCS box protein 2 (ASB-2)
Gene: ASB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30116272
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ank_2, Ank_2~Ank_3, Ank_2~Ank_4, Ank_2~SOCS_box, Ank_2~Ank_5, Ank_3~Ank_5, Ank_4~Ank_5
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 635
+	Hs
		961421 NFKB2_HUMAN (68-294): 6.66e-64: 218: 34.32		ASB2_HUMAN (1-635): 4.32e-159: 472: 100.00
+	Mm
		103608 ANK2_MOUSE (118-315): 9.6e-41: 153: 23.50		ANK3_MOUSE (2-356): 8.59e-93: 316: 21.97
+	Hs
		883496 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		ANK3_HUMAN (2-356): 3.48e-96: 326: 21.41
+	Hs
		1021462 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		ANK3_HUMAN (2-356): 3.48e-96: 326: 21.41
+	Dr
		47649 A0AR23_DANRE (6-314): 4.5e-70: 236: 21.61		ANR52_DANRE (3-325): 4.32e-51: 192: 16.47
+	Hs
		121553 IKBE_HUMAN (3-315): 1.28e-74: 239: 32.10		ANR17_HUMAN (329-613): 1.52e-45: 176: 21.28
+	Hs
		862028 DAPK1_HUMAN (27-317): 1.12e-62: 216: 17.11		ANK2_HUMAN (311-634): 7.45e-48: 183: 18.88
+	Hs
		310030 TNKS1_HUMAN (187-313): 1.98e-30: 123: 18.75		TNKS1_HUMAN (3-370): 2.81e-75: 264: 17.70
+	Hs
		121592 IKBE_HUMAN (3-315): 1.28e-74: 239: 32.10		ANKH1_HUMAN (3-171): 1.59e-23: 108: 11.83
+	Hs
		121548 IKBE_HUMAN (3-315): 1.28e-74: 239: 32.10		ANR28_HUMAN (448-616): 7.06e-15: 80.4: 9.27
+	Hs
		883487 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		ANK2_HUMAN (311-634): 7.45e-48: 183: 18.88
+	Hs
		965154 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		ANK2_HUMAN (311-634): 7.45e-48: 183: 18.88
+	Hs
		257652 ANR17_HUMAN (20-307): 2.66e-38: 146: 13.27		ANKH1_HUMAN (3-171): 1.59e-23: 108: 11.83
+	Hs
		166913 ANK2_HUMAN (118-315): 9.61e-41: 153: 23.50		ANR28_HUMAN (448-616): 7.06e-15: 80.4: 9.27
+	Hs
		166969 ANR44_HUMAN (3-219): 9.3e-39: 147: 18.50		ANR28_HUMAN (448-616): 7.06e-15: 80.4: 9.27
+	Hs
		883691 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		ASB3_HUMAN (412-568): 1.18e-15: 81.9: 15.66
+	Hs
		1330905 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		ASB3_HUMAN (412-568): 1.18e-15: 81.9: 15.66
+	Hs
		166869 TNKS1_HUMAN (187-313): 1.98e-30: 123: 18.75		ANR28_HUMAN (448-616): 7.06e-15: 80.4: 9.27
+	Hs
		166919 ANK3_HUMAN (1-130): 1.86e-30: 123: 10.77		ANR28_HUMAN (448-616): 7.06e-15: 80.4: 9.27
+	Hs
		167014 TNKS2_HUMAN (187-313): 3.7e-30: 122: 17.97		ANR28_HUMAN (448-616): 7.06e-15: 80.4: 9.27