HitPredict

Interactor 1: DNMT1 (P26358)
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT)
Gene: DNMT1

Interactor 2: EF1A1 (P68104)
Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)
Gene: EEF1A1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	21653829
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1616 Hs			1 462
+	Xl
		528444 P79922_XENLA (126-1616): 0: 1502: 70.07		EF1A0_XENLA (1-462): 0: 574: 95.89
+	Xl
		568006 P79922_XENLA (126-1616): 0: 1502: 70.07		EF1A2_XENLA (1-461): 0: 564: 91.11
+	Hs
		152824 TRDMT_HUMAN (1138-1334): 3.1e-54: 197: 23.50		EF1A1_HUMAN (1-462): 0: 578: 100.00
+	Hs
		932922 SMC3_HUMAN (112-523): 4.15e-40: 164: 12.53		EF1A1_HUMAN (1-462): 0: 578: 100.00
+	Hs
		984457 DNM3B_HUMAN (1130-1325): 2.44e-41: 167: 17.65		EF1A2_HUMAN (1-461): 0: 567: 92.63
+	Dm
		444626 NBEA_DROME (2-715): 9.32e-43: 174: 13.89		EF1A1_DROME (1-462): 0: 556: 85.71
+	Hs
		932749 NIPBL_HUMAN (4-361): 1.81e-13: 78.5: 14.14		EF1A1_HUMAN (1-462): 0: 578: 100.00