HitPredict

Interactor 1: ERBB3 (P21860)
Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)
Gene: ERBB3

Interactor 2: HBA (P69905)
Hemoglobin subunit alpha (Alpha-globin) (Hemoglobin alpha chain) [Cleaved into: Hemopressin]
Gene: HBA, HBA1;

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24189400
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1342 Hs			1 142
+	Hs
		641562 ERBB3_HUMAN (1-1342): 0: 1390: 100.00		HBG2_HUMAN (3-141): 4.21e-58: 178: 39.31
+	Hs
		380735 ERBB3_HUMAN (1-1342): 0: 1390: 100.00		HBD_HUMAN (3-141): 9.85e-57: 175: 41.38
+	Hs
		380811 ERBB3_HUMAN (1-1342): 0: 1390: 100.00		HBE_HUMAN (3-141): 1.27e-56: 175: 36.55
+	Hs
		641560 ERBB3_HUMAN (1-1342): 0: 1390: 100.00		HBB_HUMAN (3-141): 7.49e-57: 175: 42.07
+	Hs
		641561 ERBB3_HUMAN (1-1342): 0: 1390: 100.00		HBG1_HUMAN (3-141): 7.58e-57: 175: 39.31
+	Hs
		363120 EGFR_HUMAN (18-1211): 0: 1060: 40.65		HBA_HUMAN (1-142): 5.96e-59: 180: 100.00
+	Rn
		380806 INSR_RAT (330-650): 1.67e-21: 104: 17.89		HBB1_RAT (3-141): 1.52e-57: 177: 38.62
+	Rn
		380678 INSR_RAT (330-650): 1.67e-21: 104: 17.89		HBA_RAT (1-142): 1.58e-55: 172: 78.17