HitPredict

Interactor 1: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: SFR19 (Q9H7N4)
Splicing factor, arginine/serine-rich 19 (SR-related C-terminal domain-associated factor 1) (SR-related and CTD-associated factor 1) (SR-related-CTD-associated factor) (SCAF) (Serine arginine-rich pre-mRNA splicing factor SR-A1) (SR-A1)
Gene: SCAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0006397 - mRNA processing
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 475 Hs			1 1312
+	Hs
		641907 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		SCAFB_HUMAN (53-1289): 2.43e-44: 178: 13.25
+	Hs
		554269 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		MUC1_HUMAN (537-1311): 3.7e-15: 83.1: 12.58
+	Hs
		641983 U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00		SRRM2_HUMAN (450-1311): 6.2e-14: 79.5: 12.17
+	Hs
		1077481 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		SHAN3_HUMAN (96-695): 1.19e-27: 124: 16.59
+	Hs
		1020323 ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42		SHAN3_HUMAN (96-695): 1.19e-27: 124: 16.59
+	Hs
		1054314 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		MDC1_HUMAN (32-1063): 5.74e-36: 151: 9.11
+	Hs
		1077540 ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79		SRRM2_HUMAN (450-1311): 6.2e-14: 79.5: 12.17
+	Hs
		1020354 ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42		SRRM2_HUMAN (450-1311): 6.2e-14: 79.5: 12.17
+	Hs
		1054673 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		SRRM2_HUMAN (450-1311): 6.2e-14: 79.5: 12.17
+	Hs
		1037795 RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16		PRP4K_HUMAN (514-804): 6.19e-11: 69.2: 20.82
+	Hs
		1031447 PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78		SHAN3_HUMAN (96-695): 1.19e-27: 124: 16.59
+	Hs
		516677 PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35		SHAN3_HUMAN (96-695): 1.19e-27: 124: 16.59
+	Hs
		1264818 PUF60_HUMAN (92-474): 7.84e-23: 103: 21.50		TITIN_HUMAN (25-1295): 1.08e-16: 88.7: 10.37
+	Hs
		1355616 PUF60_HUMAN (92-474): 7.84e-23: 103: 21.50		SRRM2_HUMAN (450-1311): 6.2e-14: 79.5: 12.17
+	Hs
		1031405 PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78		TITIN_HUMAN (25-1295): 1.08e-16: 88.7: 10.37
+	Hs
		516609 PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35		TITIN_HUMAN (25-1295): 1.08e-16: 88.7: 10.37
+	Hs
		516595 PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35		KMT2C_HUMAN (269-1146): 5.91e-15: 82.9: 9.10
+	Hs
		516749 PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35		SRRM2_HUMAN (450-1311): 6.2e-14: 79.5: 12.17