Interactor 1: PPLA (P26678)
Cardiac phospholamban (PLB)
Gene: PLN
Interactor 2: DMPK (Q09013)
Myotonin-protein kinase (MT-PK) (EC 2.7.11.1) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase)
Gene: DMPK
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.61 | 1.00 | 0.785 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15598648 |
| Identification Methods | affinity chromatography technology, enzymatic study, protein kinase assay, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Phospholamban~Pkinase |
| Common GO terms | GO:0005789 - endoplasmic reticulum membrane GO:0006874 - intracellular calcium ion homeostasis GO:0008016 - regulation of heart contraction GO:0033017 - sarcoplasmic reticulum membrane |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
