Interactor 1: RAD53 (P22216)
Serine/threonine-protein kinase RAD53 (EC 2.7.12.1) (CHEK2 homolog) (Serine-protein kinase 1)
Gene: RAD53

Interactor 2: PP2C2 (P39966)
Protein phosphatase 2C homolog 2 (PP2C-2) (EC 3.1.3.16)
Gene: PTC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.917

The method score is based on:

Property Details
Experiments 11805837, 12667463, 17325030, 17130285, 20733106
Identification Methods anti tag coimmunoprecipitation, two hybrid, affinity chromatography technology, unspecified method
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PP2C~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 821
Sc

1 464
+ Hs
+ Rn
+ At
+ At
+ At
+ At
+ At
+ At
+ Hs
+ Rn
+ Hs
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 11Aug2025