HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: ABL2 (P42684)
Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)
Gene: ABL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~PK_Tyr_Ser-Thr
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1182
+	Hs
		789053 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ABL2_HUMAN (1-1182): 0: 1019: 100.00
+	Hs
		789056 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ABL2_HUMAN (1-1182): 0: 1019: 100.00
+	Hs
		683185 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		ABL2_HUMAN (1-1182): 0: 1019: 100.00
+	Hs
		683884 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		ABL2_HUMAN (1-1182): 0: 1019: 100.00
+	Hs
		337416 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ABL1_HUMAN (58-1182): 0: 784: 51.21
+	Hs
		337355 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ABL1_HUMAN (58-1182): 0: 784: 51.21
+	Hs
		337420 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ABL1_HUMAN (58-1182): 0: 784: 51.21
+	Hs
		337366 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		ABL1_HUMAN (58-1182): 0: 784: 51.21
+	Hs
		337367 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		ABL1_HUMAN (58-1182): 0: 784: 51.21
+	Hs
		337436 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		ABL1_HUMAN (58-1182): 0: 784: 51.21
+	Hs
		411661 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		LCK_HUMAN (56-554): 7.83e-175: 526: 38.87
+	Hs
		411605 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		LCK_HUMAN (56-554): 7.83e-175: 526: 38.87
+	Hs
		411666 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		LCK_HUMAN (56-554): 7.83e-175: 526: 38.87
+	Hs
		909481 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ITK_HUMAN (31-545): 3.51e-162: 497: 32.83
+	Hs
		782766 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CSK_HUMAN (100-546): 2.57e-156: 475: 38.46
+	Hs
		782768 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		CSK_HUMAN (100-546): 2.57e-156: 475: 38.46
+	Hs
		683181 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		CSK_HUMAN (100-546): 2.57e-156: 475: 38.46
+	Hs
		683983 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		BTK_HUMAN (61-547): 1.36e-178: 541: 37.30
+	Hs
		411616 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		LCK_HUMAN (56-554): 7.83e-175: 526: 38.87
+	Hs
		683994 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		ITK_HUMAN (31-545): 3.51e-162: 497: 32.83