Protein: H2BFS
Histone H2B type F-S (H2B-clustered histone 12 like) (H2B.S histone 1) (Histone H2B.s) (H2B/s)

Gene: H2BFS, H2BC12L
Organism: Homo sapiens
Interactions: 146
UniProt ID: P57053

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0002227 - innate immune response in mucosa
GO:0003677 - DNA binding
GO:0005615 - extracellular space
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

418907

H2A1B
Histone H2A type 1-B/E

3

20

High-throughput

0.839

High

943338

H4
Histone H4

3

20

High-throughput

0.839

High

943377

H32
Histone H3.2

3

20

High-throughput

0.827

High

591560

H2AX
Histone H2AX

2

20

High-throughput

0.776

High

943341

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

2

20

High-throughput

0.776

High

943358

H31T
Histone H3.1t

2

20

High-throughput

0.776

High

943406

H2A1H
Histone H2A type 1-H

2

20

High-throughput

0.776

High

502279

H2A1
Histone H2A type 1

2

20

High-throughput

0.754

High

507741

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

20

High-throughput

0.754

High

943401

H2B1A
Histone H2B type 1-A

2

19

High-throughput

0.754

High

943412

H2B1L
Histone H2B type 1-L

2

19

High-throughput

0.754

High

160170

CHD2
Chromodomain-helicase-DNA-binding protein 2

1

20

High-throughput

0.665

High

277620

H2AY
Core histone macro-H2A.1

1

20

High-throughput

0.665

High

501949

H2AZ
Histone H2A.Z

1

20

High-throughput

0.665

High

943378

H2AV
Histone H2A.V

1

20

High-throughput

0.665

High

943407

PWP2A
PWWP domain-containing protein 2A

1

20

High-throughput

0.665

High

943419

HIRP3
HIRA-interacting protein 3

1

20

High-throughput

0.665

High

256812

H2B1K
Histone H2B type 1-K

1

20

High-throughput

0.618

High

449693

H2B1J
Histone H2B type 1-J

1

20

High-throughput

0.618

High

507132

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

20

High-throughput

0.618

High

634012

H2A1D
Histone H2A type 1-D

1

20

High-throughput

0.618

High

659877

H2B1O
Histone H2B type 1-O

1

20

High-throughput

0.618

High

754775

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.618

High

943336

H2B1D
Histone H2B type 1-D

1

19

High-throughput

0.618

High

943339

H2B1C
Histone H2B type 1-C/E/F/G/I

1

19

High-throughput

0.618

High

943340

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

20

High-throughput

0.618

High

943344

H31
Histone H3.1

1

20

High-throughput

0.618

High

943346

H33
Histone H3.3

1

20

High-throughput

0.618

High

943359

H2A2C
Histone H2A type 2-C

1

20

High-throughput

0.618

High

943360

H2B2E
Histone H2B type 2-E

1

19

High-throughput

0.618

High

943365

H2B2F
Histone H2B type 2-F

1

19

High-throughput

0.618

High

943370

USF3
Basic helix-loop-helix domain-containing protein USF3

1

4

High-throughput

0.618

High

943372

H2A2A
Histone H2A type 2-A

1

20

High-throughput

0.618

High

943373

H3C
Histone H3.3C

1

20

High-throughput

0.618

High

943380

H2A3
Histone H2A type 3

1

20

High-throughput

0.618

High

943385

H2A2B
Histone H2A type 2-B

1

20

High-throughput

0.618

High

943391

H2B3B
Histone H2B type 3-B

1

19

High-throughput

0.618

High

943399

H2A1C
Histone H2A type 1-C

1

20

High-throughput

0.618

High

943400

H2B1H
Histone H2B type 1-H

1

19

High-throughput

0.618

High

943408

H2A1A
Histone H2A type 1-A

1

20

High-throughput

0.618

High

943409

H2B1N
Histone H2B type 1-N

1

19

High-throughput

0.618

High

943410

H2A1J
Histone H2A type 1-J

1

20

High-throughput

0.618

High

943411

H2B1M
Histone H2B type 1-M

1

19

High-throughput

0.618

High

943417

H2AJ
Histone H2A.J

1

20

High-throughput

0.618

High

426465

HMGN2
Non-histone chromosomal protein HMG-17

2

20

High-throughput

0.601

High

601608

HMGA1
High mobility group protein HMG-I/HMG-Y

2

15

High-throughput

0.601

High

943357

HMGN3
High mobility group nucleosome-binding domain-containing protein 3

2

14

High-throughput

0.601

High

943413

TEP1
Telomerase protein component 1

1

8

High-throughput

0.595

High

249734

DOK2
Docking protein 2

2

8

High-throughput

0.571

High

436637

KPCB
Protein kinase C beta type

2

20

High-throughput

0.571

High

702330

ELK4
ETS domain-containing protein Elk-4

2

12

High-throughput

0.571

High

943342

GRB2
Growth factor receptor-bound protein 2

2

18

High-throughput

0.571

High

943348

MK07
Mitogen-activated protein kinase 7

2

11

High-throughput

0.571

High

176957

CE290
Centrosomal protein of 290 kDa

1

20

High-throughput

0.515

High

424377

HMGN1
Non-histone chromosomal protein HMG-14

1

8

High-throughput

0.515

High

675433

TYY1
Transcriptional repressor protein YY1

1

12

High-throughput

0.515

High

720169

UFO
Tyrosine-protein kinase receptor UFO

1

1

High-throughput

0.515

High

833399

RGS2
Regulator of G-protein signaling 2

1

4

High-throughput

0.515

High

889361

RGS6
Regulator of G-protein signaling 6

1

2

High-throughput

0.515

High

936535

AF17
Protein AF-17

1

20

High-throughput

0.515

High

943337

RL23A
Large ribosomal subunit protein uL23

1

2

High-throughput

0.515

High

943353

MVP
Major vault protein

1

4

High-throughput

0.515

High

943354

KIF22
Kinesin-like protein KIF22

1

14

High-throughput

0.515

High

943363

PDCD4
Programmed cell death protein 4

1

8

High-throughput

0.515

High

943369

PA24F
Cytosolic phospholipase A2 zeta

1

13

High-throughput

0.515

High

943371

CDCA2
Cell division cycle-associated protein 2

1

2

High-throughput

0.515

High

943374

PRP8
Pre-mRNA-processing-splicing factor 8

1

6

High-throughput

0.515

High

943375

IYD1
Iodotyrosine deiodinase 1

1

1

High-throughput

0.515

High

943381

CHM1B
Charged multivesicular body protein 1b

1

5

High-throughput

0.515

High

943390

MIER1
Mesoderm induction early response protein 1

1

13

High-throughput

0.515

High

943396

TITIN
Titin

1

20

High-throughput

0.515

High

943397

RUBIC
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein

1

1

High-throughput

0.515

High

943404

ZN653
Zinc finger protein 653

1

4

High-throughput

0.515

High

943416

MTG1
Mitochondrial ribosome-associated GTPase 1

1

6

High-throughput

0.515

High

943429

OCTC
Peroxisomal carnitine O-octanoyltransferase

1

1

High-throughput

0.515

High

943430

PLAL2
Zinc finger protein PLAGL2

1

2

High-throughput

0.515

High

160877

STX16
Syntaxin-16

1

0

High-throughput

0.493

High

660253

BDNF
Neurotrophic factor BDNF precursor form

1

0

High-throughput

0.493

High

943351

C1D
Nuclear nucleic acid-binding protein C1D

1

0

High-throughput

0.493

High

943431

SHOC2
Leucine-rich repeat protein SHOC-2

1

0

High-throughput

0.493

High

943432

CLCA2
Calcium-activated chloride channel regulator 2

1

0

High-throughput

0.493

High

137425

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

20

High-throughput

0.479

High

157148

CTRO
Citron Rho-interacting kinase

1

17

High-throughput

0.479

High

222863

PRC1
Protein regulator of cytokinesis 1

1

9

High-throughput

0.479

High

286766

SKAP2
Src kinase-associated phosphoprotein 2

1

6

High-throughput

0.479

High

324683

HEXI1
Protein HEXIM1

1

14

High-throughput

0.479

High

330798

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

386455

SPTA1
Spectrin alpha chain, erythrocytic 1

1

13

High-throughput

0.479

High

542404

TOP2A
DNA topoisomerase 2-alpha

1

15

High-throughput

0.479

High

571662

HCLS1
Hematopoietic lineage cell-specific protein

1

20

High-throughput

0.479

High

660566

IF4B
Eukaryotic translation initiation factor 4B

1

13

High-throughput

0.479

High

775737

CYLC1
Cylicin-1

1

20

High-throughput

0.479

High

943343

1433Z
14-3-3 protein zeta/delta

1

12

High-throughput

0.479

High

943345

RED1
Double-stranded RNA-specific editase 1

1

14

High-throughput

0.479

High

943347

MYPC1
Myosin-binding protein C, slow-type

1

17

High-throughput

0.479

High

943350

TARB1
tRNA

1

2

High-throughput

0.479

High

943352

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

20

Small-scale

0.479

High

943355

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

943356

KIF14
Kinesin-like protein KIF14

1

16

High-throughput

0.479

High

943362

LARP7
La-related protein 7

1

20

High-throughput

0.479

High

943367

TEX35
Testis-expressed protein 35

1

12

High-throughput

0.479

High

943368

SMBT2
Scm-like with four MBT domains protein 2

1

20

High-throughput

0.479

High

943379

MEPCE
7SK snRNA methylphosphate capping enzyme

1

14

High-throughput

0.479

High

943383

DPPA2
Developmental pluripotency-associated protein 2

1

10

High-throughput

0.479

High

943387

SLF2
SMC5-SMC6 complex localization factor protein 2

1

1

High-throughput

0.479

High

943393

SYNPO
Synaptopodin

1

20

High-throughput

0.479

High

943395

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

2

High-throughput

0.479

High

943403

CHM4C
Charged multivesicular body protein 4c

1

9

High-throughput

0.479

High

943414

JPH2
Junctophilin-2

1

9

High-throughput

0.479

High

943415

RIOK1
Serine/threonine-protein kinase RIO1

1

12

High-throughput

0.479

High

943422

CPAP
Centrosomal P4.1-associated protein

1

13

High-throughput

0.479

High

943423

DUOX2
Dual oxidase 2

1

12

High-throughput

0.479

High

943424

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

20

High-throughput

0.479

High

943433

TENN
Tenascin-N

1

20

High-throughput

0.479

High

943435

AXIN2
Axin-2

1

4

High-throughput

0.479

High

943366

MORN1
MORN repeat-containing protein 1

1

9

High-throughput

0.470

High

943382

OVCH1
Ovochymase-1

1

1

High-throughput

0.470

High

943384

URP2
Fermitin family homolog 3

1

2

High-throughput

0.470

High

943389

AGRF5
Adhesion G protein-coupled receptor F5

1

2

High-throughput

0.470

High

943405

COX42
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial

1

1

High-throughput

0.470

High

943418

SPON2
Spondin-2

1

3

High-throughput

0.470

High

943420

RFIP5
Rab11 family-interacting protein 5

1

20

High-throughput

0.470

High

943421

CAD19
Cadherin-19

1

12

High-throughput

0.470

High

943425

FAIM1
Fas apoptotic inhibitory molecule 1

1

2

High-throughput

0.470

High

943428

DYH1
Dynein axonemal heavy chain 1

1

12

High-throughput

0.470

High

943434

DLGP4
Disks large-associated protein 4

1

4

High-throughput

0.470

High

136185

LST1
Leukocyte-specific transcript 1 protein

1

0

High-throughput

0.458

High

943364

ZN311
Zinc finger protein 311

1

0

High-throughput

0.458

High

389194

FINC
Fibronectin

1

20

High-throughput

0.445

High

934344

TERA
Transitional endoplasmic reticulum ATPase

1

6

High-throughput

0.445

High

943398

ESR2
Estrogen receptor beta

1

10

High-throughput

0.445

High

943335

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

9

High-throughput

0.437

High

943349

CD5R2
Cyclin-dependent kinase 5 activator 2

1

12

High-throughput

0.437

High

943361

KNOP1
Lysine-rich nucleolar protein 1

1

8

High-throughput

0.437

High

943376

ZN474
Zinc finger protein 474

1

10

High-throughput

0.437

High

943386

DYH10
Dynein axonemal heavy chain 10

1

12

High-throughput

0.437

High

943392

RHG24
Rho GTPase-activating protein 24

1

15

High-throughput

0.437

High

943394

FA47B
Protein FAM47B

1

20

High-throughput

0.437

High

943427

ARMX1
Armadillo repeat-containing X-linked protein 1

1

1

High-throughput

0.437

High

943436

PCLO
Protein piccolo

1

20

High-throughput

0.437

High

48860

ESYT3
Extended synaptotagmin-3

1

0

High-throughput

0.269

Low

49551

TMM82
Transmembrane protein 82

1

0

High-throughput

0.269

Low

943388

IHO1
Interactor of HORMAD1 protein 1

1

0

High-throughput

0.269

Low

943402

SYTL4
Synaptotagmin-like protein 4

1

0

High-throughput

0.269

Low

943426

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.269

Low

932400

GALC
Galactocerebrosidase

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025