HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29844126, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 2517
+	Hs
		909937 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		927430 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		817874 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		817898 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		927045 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MDC1_HUMAN (1380-2408): 4.76e-21: 104: 10.30
+	Hs
		297821 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		K0754_HUMAN (2168-2515): 4.87e-18: 94.2: 13.88
+	Hs
		297824 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		K0754_HUMAN (2168-2515): 4.87e-18: 94.2: 13.88
+	Hs
		297815 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		K0754_HUMAN (2168-2515): 4.87e-18: 94.2: 13.88
+	Hs
		910167 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		311800 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		TACC2_HUMAN (431-1617): 6.21e-10: 67.5: 8.62
+	Hs
		909712 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		OTOG_HUMAN (811-1320): 6.38e-10: 67.4: 14.67
+	Hs
		909455 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ANK2_HUMAN (535-2225): 4.48e-09: 64.6: 9.78
+	Hs
		647025 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		OTOG_HUMAN (811-1320): 6.38e-10: 67.4: 14.67
+	Hs
		927666 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		311801 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		TACC2_HUMAN (431-1617): 6.21e-10: 67.5: 8.62
+	Hs
		927196 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		OTOG_HUMAN (811-1320): 6.38e-10: 67.4: 14.67
+	Hs
		647151 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		TITIN_HUMAN (609-1544): 3.51e-09: 65.2: 9.85
+	Hs
		646808 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ANK2_HUMAN (535-2225): 4.48e-09: 64.6: 9.78
+	Hs
		927352 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		TITIN_HUMAN (609-1544): 3.51e-09: 65.2: 9.85
+	Hs
		926936 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ANK2_HUMAN (535-2225): 4.48e-09: 64.6: 9.78