HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: UBP22 (Q9UPT9)
Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22)
Gene: USP22

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 525
+	Hs
		982625 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		UBP22_HUMAN (1-525): 0: 549: 100.00
+	Hs
		777027 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		UBP8_HUMAN (116-517): 3.79e-99: 325: 28.14
+	Hs
		647288 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		UBP42_HUMAN (153-520): 5.41e-100: 330: 27.37
+	Hs
		927542 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		UBP42_HUMAN (153-520): 5.41e-100: 330: 27.37
+	Mm
		910281 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		UBP8_MOUSE (116-517): 2.54e-97: 319: 26.98
+	Hs
		646698 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		UBP8_HUMAN (116-517): 3.79e-99: 325: 28.14
+	Hs
		777029 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		UBP8_HUMAN (116-517): 3.79e-99: 325: 28.14
+	Hs
		683179 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		UBP8_HUMAN (116-517): 3.79e-99: 325: 28.14
+	Hs
		910137 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		UBP21_HUMAN (174-518): 1.8e-94: 300: 27.42
+	Hs
		927636 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		UBP21_HUMAN (174-518): 1.8e-94: 300: 27.42
+	Hs
		905373 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		UBP46_HUMAN (155-521): 9.16e-89: 278: 25.44
+	Hs
		905375 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		UBP46_HUMAN (155-521): 9.16e-89: 278: 25.44
+	Hs
		259266 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		UBP12_HUMAN (155-521): 6.15e-90: 282: 25.44
+	Hs
		683244 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		UBP46_HUMAN (155-521): 9.16e-89: 278: 25.44
+	Hs
		683881 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		UBP8_HUMAN (116-517): 3.79e-99: 325: 28.14
+	Hs
		777034 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		UBP8_HUMAN (116-517): 3.79e-99: 325: 28.14
+	Hs
		982605 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		UBP21_HUMAN (174-518): 1.8e-94: 300: 27.42
+	Mm
		935490 1433F_MOUSE (2-242): 4.62e-106: 308: 71.43		UBP39_MOUSE (10-524): 2.37e-88: 284: 17.38
+	Hs
		259277 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		UBP12_HUMAN (155-521): 6.15e-90: 282: 25.44
+	Hs
		905377 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		UBP46_HUMAN (155-521): 9.16e-89: 278: 25.44