HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: SMAG1 (Q9UPU9)
Protein Smaug homolog 1 (Smaug 1) (hSmaug1) (Sterile alpha motif domain-containing protein 4A) (SAM domain-containing protein 4A)
Gene: SAMD4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	30833792, 33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 718
+	Hs
		910163 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		SMAG1_HUMAN (1-718): 0: 1225: 100.00
+	Hs
		927663 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		SMAG1_HUMAN (1-718): 0: 1225: 100.00
+	Hs
		683817 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		SMAG1_HUMAN (1-718): 0: 1225: 100.00
+	Hs
		684399 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		SMAG1_HUMAN (1-718): 0: 1225: 100.00
+	Hs
		982626 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		SMAG1_HUMAN (1-718): 0: 1225: 100.00
+	Hs
		909642 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		SMAG2_HUMAN (1-718): 0: 1065: 61.69
+	Hs
		646959 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		SMAG2_HUMAN (1-718): 0: 1065: 61.69
+	Hs
		927124 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		SMAG2_HUMAN (1-718): 0: 1065: 61.69
+	Hs
		683407 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		SMAG2_HUMAN (1-718): 0: 1065: 61.69
+	Hs
		684087 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		SMAG2_HUMAN (1-718): 0: 1065: 61.69
+	Hs
		982093 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		SMAG2_HUMAN (1-718): 0: 1065: 61.69
+	Hs
		904666 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		SMAG2_HUMAN (1-718): 0: 1065: 61.69
+	Hs
		647094 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		Q8IXP7_HUMAN (352-709): 0: 566: 58.56
+	Hs
		927281 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		Q8IXP7_HUMAN (352-709): 0: 566: 58.56
+	Hs
		683529 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		Q8IXP7_HUMAN (352-709): 0: 566: 58.56
+	Hs
		102393 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		G3V2R1_HUMAN (410-718): 1.81e-172: 499: 89.57
+	Hs
		102398 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		G3V2R1_HUMAN (410-718): 1.81e-172: 499: 89.57
+	Hs
		102394 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		G3V2R1_HUMAN (410-718): 1.81e-172: 499: 89.57
+	Hs
		102400 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		G3V2R1_HUMAN (410-718): 1.81e-172: 499: 89.57
+	Hs
		102396 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		G3V2R1_HUMAN (410-718): 1.81e-172: 499: 89.57