HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: TLN1 (Q9Y490)
Talin-1
Gene: TLN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15161933
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 2541
+	Hs
		910159 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MACF1_HUMAN (404-2519): 9.43e-159: 555: 11.11
+	Hs
		647380 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MACF1_HUMAN (404-2519): 9.43e-159: 555: 11.11
+	Hs
		910185 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		E41L3_HUMAN (78-1116): 3.01e-115: 397: 11.42
+	Hs
		647400 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		E41L3_HUMAN (78-1116): 3.01e-115: 397: 11.42
+	Hs
		663970 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PTN4_HUMAN (61-728): 1.45e-108: 373: 13.45
+	Hs
		646653 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PTN4_HUMAN (61-728): 1.45e-108: 373: 13.45
+	Hs
		640229 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PTN3_HUMAN (54-700): 4.26e-96: 336: 16.03
+	Hs
		640212 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PTN3_HUMAN (54-700): 4.26e-96: 336: 16.03
+	Hs
		647300 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		E41L5_HUMAN (50-684): 9.18e-98: 335: 13.72
+	Hs
		909614 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PTN21_HUMAN (64-973): 1.47e-87: 316: 12.49
+	Hs
		910025 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		E41L1_HUMAN (16-610): 1.8e-85: 303: 12.87
+	Hs
		647274 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		E41L1_HUMAN (16-610): 1.8e-85: 303: 12.87
+	Hs
		547003 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		EZRI_HUMAN (84-666): 2.76e-85: 294: 14.65
+	Hs
		640086 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MOES_HUMAN (163-404): 1.04e-51: 195: 23.05
+	Hs
		646909 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PLEC_HUMAN (730-2529): 2.6e-23: 111: 12.52
+	Mm
		926889 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		PLEC_MOUSE (1236-2541): 1.84e-21: 105: 11.15
+	Hs
		728460 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYH11_HUMAN (1730-2541): 1.31e-15: 86: 8.70
+	Hs
		909464 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DYST_HUMAN (422-2075): 3.73e-15: 84.9: 9.63
+	Hs
		646685 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH11_HUMAN (1730-2541): 1.31e-15: 86: 8.70
+	Hs
		646817 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DYST_HUMAN (422-2075): 3.73e-15: 84.9: 9.63