HitPredict

Interactor 1: AP2B (P27351)
AP-2 complex subunit beta (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Clathrin assembly protein large beta chain)
Gene: APL1

Interactor 2: EDE1 (P34216)
EH domain-containing and endocytosis protein 1 (Bud site selection protein 15)
Gene: EDE1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19822444
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005935 - cellular bud neck GO:0006897 - endocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 700 Sc			1 1381
+	Hs
		724758 AP2B1_HUMAN (1-699): 0: 583: 27.89		MYH9_HUMAN (562-1329): 1.43e-32: 140: 9.13
+	Hs
		925970 AP2B1_HUMAN (1-699): 0: 583: 27.89		REPS1_HUMAN (2-488): 7.74e-23: 107: 13.19
+	Hs
		925876 AP2B1_HUMAN (1-699): 0: 583: 27.89		ITSN1_HUMAN (753-1128): 2.65e-16: 87.3: 12.27
+	Hs
		926031 AP2B1_HUMAN (1-699): 0: 583: 27.89		ITSN2_HUMAN (825-1202): 1.33e-15: 85: 9.44
+	Rn
		923861 AP2B1_RAT (1-699): 0: 583: 27.89		ITSN1_RAT (719-1084): 1.45e-14: 81.5: 12.86
+	Hs
		1014062 AP1B1_HUMAN (1-700): 0: 556: 26.69		REPS1_HUMAN (2-488): 7.74e-23: 107: 13.19
+	Hs
		926038 AP2B1_HUMAN (1-699): 0: 583: 27.89		EP15R_HUMAN (849-1039): 2.63e-13: 76.9: 8.38
+	Hs
		787890 AP2B1_HUMAN (1-699): 0: 583: 27.89		EPS15_HUMAN (583-757): 7.71e-11: 68.8: 14.86
+	Mm
		788007 AP2B1_MOUSE (1-699): 0: 583: 27.89		EPS15_MOUSE (786-953): 2.57e-09: 64.2: 10.59
+	Rn
		923853 AP2B1_RAT (1-699): 0: 583: 27.89		Q5JC29_RAT (692-854): 2.58e-09: 63.8: 12.58
+	Hs
		1014017 AP1B1_HUMAN (1-700): 0: 556: 26.69		ITSN1_HUMAN (753-1128): 2.65e-16: 87.3: 12.27
+	Hs
		1014096 AP1B1_HUMAN (1-700): 0: 556: 26.69		ITSN2_HUMAN (825-1202): 1.33e-15: 85: 9.44
+	Ce
		1341625 Q9N4F3_CAEEL (1-657): 0: 543: 28.29		Q9U2T9_CAEEL (8-269): 1.42e-19: 97.7: 17.53
+	Dm
		112643 Q24253_DROME (1-634): 0: 548: 28.64		M9NDL7_DROME (2-624): 6.22e-16: 85.7: 9.79
+	Hs
		1014098 AP1B1_HUMAN (1-700): 0: 556: 26.69		EP15R_HUMAN (849-1039): 2.63e-13: 76.9: 8.38
+	Hs
		787903 AP1B1_HUMAN (1-700): 0: 556: 26.69		EPS15_HUMAN (583-757): 7.71e-11: 68.8: 14.86
+	Hs
		212604 AP1G1_HUMAN (5-692): 3.91e-164: 494: 11.38		EPS15_HUMAN (583-757): 7.71e-11: 68.8: 14.86
+	Rn
		88768 D3ZUY8_RAT (1-665): 3.01e-153: 470: 13.98		ITSN1_RAT (719-1084): 1.45e-14: 81.5: 12.86
+	Rn
		88764 D3ZUY8_RAT (1-665): 3.01e-153: 470: 13.98		Q5JC29_RAT (692-854): 2.58e-09: 63.8: 12.58
+	Rn
		1126749 Q66HM2_RAT (1-639): 1.7e-151: 465: 15.47		Q5JC29_RAT (692-854): 2.58e-09: 63.8: 12.58