Protein: ARHG3
Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN)

Gene: ARHG3, ARHGEF3
Organism: Homo sapiens
Interactions: 15
UniProt ID: Q9NR81

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0007266 - Rho protein signal transduction
GO:0035025 - positive regulation of Rho protein signal transduction
GO:0051056 - regulation of small GTPase mediated signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

537087

TRI27
Zinc finger protein RFP

5

4

High-throughput

0.722

High

900948

RHOA
Transforming protein RhoA

1

20

Small-scale

0.692

High

916002

RHOB
Rho-related GTP-binding protein RhoB

1

20

Small-scale

0.692

High

1245792

CEP70
Centrosomal protein of 70 kDa

4

0

High-throughput

0.675

High

734785

TRI23
E3 ubiquitin-protein ligase TRIM23

3

4

High-throughput

0.617

High

253202

HSF2B
Heat shock factor 2-binding protein

2

1

High-throughput

0.606

High

1344366

PICK1
PRKCA-binding protein

2

1

High-throughput

0.606

High

894481

CDC42
Cell division control protein 42 homolog

1

20

Small-scale

0.590

High

869754

TERF1
Telomeric repeat-binding factor 1

2

1

High-throughput

0.553

High

851694

NEK4
Serine/threonine-protein kinase Nek4

1

13

High-throughput

0.536

High

163333

XPO1
Exportin-1

1

10

High-throughput

0.479

High

228806

PRKN
E3 ubiquitin-protein ligase parkin

1

15

High-throughput

0.479

High

1298210

ZDH15
Palmitoyltransferase ZDHHC15

1

1

Small-scale

0.437

High

1317416

PBX4
Pre-B-cell leukemia transcription factor 4

2

0

High-throughput

0.316

High

1287673

DDT4L
DNA damage-inducible transcript 4-like protein

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024