HitPredict

Interactor 1: H1T (P22492)
Histone H1t (Testicular H1 histone)
Gene: H1-6

Interactor 2: H33 (P84243)
Histone H3.3
Gene: H3-3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	35575683, 33961781, 29044188
Identification Methods	cross-linking study, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~Linker_histone
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0006334 - nucleosome assembly GO:0030527 - structural constituent of chromatin GO:0031492 - nucleosomal DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 207 Hs			1 136
+	Hs
		998328 SHPRH_HUMAN (4-191): 4.62e-69: 230: 20.00		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		1016869 SHPRH_HUMAN (4-191): 4.62e-69: 230: 20.00		H33_HUMAN (1-136): 1.13e-59: 182: 100.00
+	Hs
		883543 SHPRH_HUMAN (4-191): 4.62e-69: 230: 20.00		CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76
+	Hs
		649293 H1T_HUMAN (1-207): 1.89e-40: 138: 100.00		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		649324 H1T_HUMAN (1-207): 1.89e-40: 138: 100.00		H31T_HUMAN (1-136): 2.59e-59: 181: 93.38
+	Hs
		649347 H1T_HUMAN (1-207): 1.89e-40: 138: 100.00		H32_HUMAN (1-136): 5.34e-59: 180: 97.06
+	Hs
		649337 H1T_HUMAN (1-207): 1.89e-40: 138: 100.00		H3C_HUMAN (1-136): 2e-56: 173: 95.59
+	Hs
		595389 H15_HUMAN (1-119): 6.26e-20: 85.9: 59.66		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		595739 H13_HUMAN (1-150): 6.93e-20: 85.5: 49.33		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		595395 H15_HUMAN (1-119): 6.26e-20: 85.9: 59.66		H33_HUMAN (1-136): 1.13e-59: 182: 100.00
+	Hs
		595741 H13_HUMAN (1-150): 6.93e-20: 85.5: 49.33		H33_HUMAN (1-136): 1.13e-59: 182: 100.00
+	Hs
		595442 H15_HUMAN (1-119): 6.26e-20: 85.9: 59.66		H31T_HUMAN (1-136): 2.59e-59: 181: 93.38
+	Hs
		595788 H13_HUMAN (1-150): 6.93e-20: 85.5: 49.33		H31T_HUMAN (1-136): 2.59e-59: 181: 93.38
+	Hs
		595484 H15_HUMAN (1-119): 6.26e-20: 85.9: 59.66		H32_HUMAN (1-136): 5.34e-59: 180: 97.06
+	Hs
		595807 H13_HUMAN (1-150): 6.93e-20: 85.5: 49.33		H32_HUMAN (1-136): 5.34e-59: 180: 97.06
+	Hs
		596039 H12_HUMAN (33-150): 3.14e-18: 80.9: 55.93		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		596043 H12_HUMAN (33-150): 3.14e-18: 80.9: 55.93		H33_HUMAN (1-136): 1.13e-59: 182: 100.00
+	Hs
		595476 H15_HUMAN (1-119): 6.26e-20: 85.9: 59.66		H3C_HUMAN (1-136): 2e-56: 173: 95.59
+	Hs
		595801 H13_HUMAN (1-150): 6.93e-20: 85.5: 49.33		H3C_HUMAN (1-136): 2e-56: 173: 95.59
+	Hs
		595996 H12_HUMAN (33-150): 3.14e-18: 80.9: 55.93		CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76