HitPredict

Interactor 1: P121C (A8CG34)
Nuclear envelope pore membrane protein POM 121C (Nuclear pore membrane protein 121-2) (POM121-2) (Pore membrane protein of 121 kDa C)
Gene: POM121C

Interactor 2: IMA3 (O00629)
Importin subunit alpha-3 (Importin alpha Q1) (Qip1) (Karyopherin subunit alpha-4)
Gene: KPNA4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore GO:0005654 - nucleoplasm GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding GO:0031965 - nuclear membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1229 Hs			1 521
+	Hs
		65033 P121C_HUMAN (1-1229): 1.48e-89: 317: 100.00		IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80
+	Hs
		134948 P121A_HUMAN (1-1229): 8.01e-79: 286: 93.69		IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00
+	Hs
		131490 P121A_HUMAN (1-1229): 8.01e-79: 286: 93.69		IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80
+	Hs
		65040 P121C_HUMAN (1-1229): 1.48e-89: 317: 100.00		IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62
+	Hs
		853423 P121A_HUMAN (1-1229): 8.01e-79: 286: 93.69		IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62
+	Hs
		238723 P121A_HUMAN (1-1229): 8.01e-79: 286: 93.69		IMA7_HUMAN (1-521): 3.56e-142: 421: 46.46
+	Hs
		72691 B4DET5_HUMAN (5-742): 3.52e-12: 72.9: 9.72		IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00
+	Hs
		131460 ANR11_HUMAN (157-904): 2.53e-12: 73.8: 10.21		IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80
+	Hs
		72690 B4DET5_HUMAN (5-742): 3.52e-12: 72.9: 9.72		IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80
+	Hs
		853331 POZP3_HUMAN (243-348): 3.32e-26: 109: 76.64		IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62
+	Hs
		131388 NU214_HUMAN (91-936): 1.02e-10: 68.8: 10.61		IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80
+	Hs
		72719 B4DET5_HUMAN (5-742): 3.52e-12: 72.9: 9.72		IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62
+	Hs
		238693 ANR11_HUMAN (157-904): 2.53e-12: 73.8: 10.21		IMA7_HUMAN (1-521): 3.56e-142: 421: 46.46
+	Xl
		852372 Q5EWX9_XENLA (279-1229): 4.98e-12: 72.7: 13.89		IMA5_XENLA (3-521): 3.77e-135: 403: 47.71