HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 480
+	Hs
		650467 RFA1_HUMAN (1-616): 0: 781: 100.00		AKT2_HUMAN (1-477): 0: 559: 81.21
+	Hs
		566294 RFA1_HUMAN (1-616): 0: 781: 100.00		KPCA_HUMAN (14-477): 1.41e-151: 448: 36.27
+	Hs
		616673 RFA1_HUMAN (1-616): 0: 781: 100.00		KS6B1_HUMAN (132-479): 4.01e-147: 432: 43.75
+	Hs
		568552 RFA1_HUMAN (1-616): 0: 781: 100.00		KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53
+	Hs
		650723 RFA1_HUMAN (1-616): 0: 781: 100.00		KS6A3_HUMAN (36-455): 4.1e-103: 325: 23.01
+	Hs
		650566 RFA1_HUMAN (1-616): 0: 781: 100.00		KPCI_HUMAN (139-474): 7.46e-101: 316: 45.53
+	Hs
		651283 RFA1_HUMAN (1-616): 0: 781: 100.00		KS6A1_HUMAN (85-407): 6.15e-92: 296: 26.39